Human Nasal Turbinate Tissues in Organ Culture as a Model for Human Cytomegalovirus Infection at the Mucosal Entry Site.
human cytomegalovirus
nasal turbinates
organ culture
viral mucosal entry site
Journal
Journal of virology
ISSN: 1098-5514
Titre abrégé: J Virol
Pays: United States
ID NLM: 0113724
Informations de publication
Date de publication:
15 09 2020
15 09 2020
Historique:
received:
23
06
2020
accepted:
14
07
2020
pubmed:
31
7
2020
medline:
22
12
2020
entrez:
31
7
2020
Statut:
epublish
Résumé
The initial events of viral infection at the primary mucosal entry site following horizontal person-to-person transmission have remained ill defined. Our limited understanding is further underscored by the absence of animal models in the case of human-restricted viruses, such as human cytomegalovirus (HCMV), a leading cause of congenital infection and a major pathogen in immunocompromised individuals. Here, we established a novel
Identifiants
pubmed: 32727881
pii: JVI.01258-20
doi: 10.1128/JVI.01258-20
pmc: PMC7495380
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 American Society for Microbiology.
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