A case of toxic epidermal necrosis-like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report.
Dermatology
acute syndrome of apoptotic pan-epidermolysis
systemic lupus erythematosus
toxic epidermal necrolysis
Journal
SAGE open medical case reports
ISSN: 2050-313X
Titre abrégé: SAGE Open Med Case Rep
Pays: England
ID NLM: 101638686
Informations de publication
Date de publication:
2020
2020
Historique:
received:
11
05
2020
accepted:
05
06
2020
entrez:
31
7
2020
pubmed:
31
7
2020
medline:
31
7
2020
Statut:
epublish
Résumé
We present a rare case of a 61-year-old woman presenting with a widespread erosive eruption on her torso and extremities. Although the lesions were histologically compatible with toxic epidermal necrolysis, clinically the patient was hemodynamically stable, had no mucosal involvement and had no relevant medical history or potentially incriminating medications. Further investigations uncovered a new diagnosis of systemic lupus erythematosus, with this toxic epidermal necrolysis-like eruption being the first presentation of the disease. This case highlights the importance of broadening the differential diagnosis in patients presenting with acute widespread cleavage of the epidermis, using the spectrum of acute syndrome of apoptotic pan-epidermolysis as a reference.
Identifiants
pubmed: 32728443
doi: 10.1177/2050313X20940420
pii: 10.1177_2050313X20940420
pmc: PMC7364792
doi:
Types de publication
Case Reports
Langues
eng
Pagination
2050313X20940420Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Références
J Am Acad Dermatol. 2003 Apr;48(4):525-9
pubmed: 12664014
Pathol Biol (Paris). 2015 Sep;63(4-5):222-3
pubmed: 26088436
Indian J Dermatol. 2014 Jul;59(4):401-2
pubmed: 25071264
Clin Cosmet Investig Dermatol. 2019 Sep 04;12:653-667
pubmed: 31564947
Lupus. 2011 May;20(6):647-52
pubmed: 21148602
Asian Pac J Allergy Immunol. 2012 Mar;30(1):83-7
pubmed: 22523912
Arthritis Rheum. 2012 Aug;64(8):2677-86
pubmed: 22553077
Dermatol Online J. 2017 Jul 15;23(7):
pubmed: 29469697
J Am Acad Dermatol. 2013 May;68(5):693.e1-14; quiz 706-8
pubmed: 23602182
J Eur Acad Dermatol Venereol. 2019 Sep;33(9):1685-1694
pubmed: 31087464
Lupus. 2004;13(12):941-50
pubmed: 15645750
J Clin Rheumatol. 2014 Apr;20(3):167-71
pubmed: 24662561
Ann Dermatol. 2016 Feb;28(1):117-8
pubmed: 26848232
J Cutan Med Surg. 2001 Nov-Dec;5(6):479-85
pubmed: 11907856
Dermatol Online J. 2018 May 15;24(5):
pubmed: 30142736