Non-invasive assessment of liver fibrosis in alcoholic liver disease.
alcoholic liver disease
cirrhosis
fibrosis
transient elastography
Journal
Clinical and experimental hepatology
ISSN: 2392-1099
Titre abrégé: Clin Exp Hepatol
Pays: Poland
ID NLM: 101703431
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
09
01
2020
accepted:
08
03
2020
entrez:
31
7
2020
pubmed:
31
7
2020
medline:
31
7
2020
Statut:
ppublish
Résumé
To assess the severity of fibrosis in patients with alcoholic liver disease (ALD) by a non-invasive method (transient elastography - TE). A cross sectional study was conducted on 130 cases of ALD over a period of 2 years. Upper gastrointestinal (GI) endoscopy and transient elastography were done. Liver fibrosis was staged with the METAVIR system and severity of fibrosis was correlated with complications, duration of alcohol abuse, aspartate transaminase (AST) to platelet ratio index (APRI) and Child-Turcotte-Pugh (CTP) score. To establish the relationship between various parameters, Spearman's correlation coefficient ( Distribution in 130 patients according to the METAVIR stage (median liver stiffness measurement [LSM]) was: F0: TE is an inexpensive and non-invasive modality to assess the severity of liver fibrosis in ALD. It can be used as a good screening tool to identify patients with cirrhosis without the use of invasive liver biopsy, enabling better prognostication for the development of complications.
Identifiants
pubmed: 32728629
doi: 10.5114/ceh.2020.95739
pii: 40778
pmc: PMC7380467
doi:
Types de publication
Journal Article
Langues
eng
Pagination
125-130Informations de copyright
Copyright © 2020 Clinical and Experimental Hepatology.
Déclaration de conflit d'intérêts
The authors report no conflict of interest.
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