What GDPR and the Health Research Regulations (HRRs) mean for Ireland: a research perspective.


Journal

Irish journal of medical science
ISSN: 1863-4362
Titre abrégé: Ir J Med Sci
Pays: Ireland
ID NLM: 7806864

Informations de publication

Date de publication:
May 2021
Historique:
received: 15 07 2020
accepted: 23 07 2020
pubmed: 31 7 2020
medline: 1 5 2021
entrez: 31 7 2020
Statut: ppublish

Résumé

Irish Health Research Regulations (HRRs) were introduced following the European Union (EU) General Data Protection Regulation (GDPR) in 2018. The HRRs described specific supplementary regulatory requirements for research regarding governance, processes and procedure that impact on several facets of research. The numerous problems that the HRRs and particularly "explicit consent" inadvertently created were presented under the auspices of the Irish Academy of Medical Sciences (IAMS) on November 25, 2019, at the Royal College of Surgeons in Ireland. The objective of this review was to obtain feedback and to examine the impact of GDPR and the HRRs on health research in Ireland in order to determine whether the preliminary feedback, presented at the IAMS meetings, was reflected at a national level. Individuals from the research community were invited to provide feedback on the impact, if any, of the HRRs on health research. Retrospective patient recruitment and consent outside a hospital setting for a multi-institutional Breast Predict study (funded by the Irish Cancer Society) were also analysed. Feedback replicated the issues presented at the IAMS with additional concerns identified. Only 20% of the original target population (n = 1987) could be included in the Breast Predict study. Our results confirm that the HRRs have had a significantly negative impact on health research in Ireland. Urgent meaningful engagement between patient advocate groups, the research community and legislators would help ameliorate these impacts.

Sections du résumé

BACKGROUND BACKGROUND
Irish Health Research Regulations (HRRs) were introduced following the European Union (EU) General Data Protection Regulation (GDPR) in 2018. The HRRs described specific supplementary regulatory requirements for research regarding governance, processes and procedure that impact on several facets of research. The numerous problems that the HRRs and particularly "explicit consent" inadvertently created were presented under the auspices of the Irish Academy of Medical Sciences (IAMS) on November 25, 2019, at the Royal College of Surgeons in Ireland.
AIMS OBJECTIVE
The objective of this review was to obtain feedback and to examine the impact of GDPR and the HRRs on health research in Ireland in order to determine whether the preliminary feedback, presented at the IAMS meetings, was reflected at a national level.
METHODS METHODS
Individuals from the research community were invited to provide feedback on the impact, if any, of the HRRs on health research. Retrospective patient recruitment and consent outside a hospital setting for a multi-institutional Breast Predict study (funded by the Irish Cancer Society) were also analysed.
RESULTS RESULTS
Feedback replicated the issues presented at the IAMS with additional concerns identified. Only 20% of the original target population (n = 1987) could be included in the Breast Predict study.
CONCLUSIONS CONCLUSIONS
Our results confirm that the HRRs have had a significantly negative impact on health research in Ireland. Urgent meaningful engagement between patient advocate groups, the research community and legislators would help ameliorate these impacts.

Identifiants

pubmed: 32728834
doi: 10.1007/s11845-020-02330-3
pii: 10.1007/s11845-020-02330-3
pmc: PMC8049920
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

505-514

Références

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General Data Protection Regulation (GDPR). Recitals. Key Issues. gdpr-info.eu. EU: c2019 [cited 20 April 2020]. Available from: https://gdpr-info.eu/
Clarke N, Vale G, Reeves EP et al (2019) GDPR: an impediment to research? Ir J Med Sci 188:1129–1135. https://doi.org/10.1007/s11845-019-01980-2
doi: 10.1007/s11845-019-01980-2 pubmed: 30734900
Data Protection Act 2018 (Section 36(2)) (Health Research) Regulations 2018. irishstatutebook.ie. Ireland:c2019 [cited 20 April 2020].Available from: http://www.irishstatutebook.ie/eli/2018/si/314/made/en/pdf
Health Research Consent declaration Committee. Hrcdc.ie. Ireland: c2019 [cited 20 April 2020]. Available from: https://hrcdc.ie/
Health Research Board Decision Tree. hrb.ie. Ireland: c2019 [cited 20 April 2020]. Available from: https://www.hrb.ie/fileadmin/user_upload/Decision_Tree_30072018.pdf
Guidance notes to support and application to process or further process personal data for the purposes of health research commencing before 8 August 2018 (re-consenting). hrcdc.ie. Ireland. c2019 [cited 20 April 2020]. Available from: https://hrcdc.ie/wp-content/uploads/2018/12/HRCDC-Guidance_Re-consenting.pdf
Woods K (2019) Researchers: consent rules put future medical trials at risk. Sunday Business Post (Ireland). Sect. A:6 (col. 1)
Mee B, Gaffney E, Glynn SA et al (2013) Development and progress of Ireland's biobank network: ethical, legal, and social implications (ELSI), standardized documentation, sample and data release, and international perspective. Biopreserv Biobank 11(1):3–11. https://doi.org/10.1089/bio.2012.0028
doi: 10.1089/bio.2012.0028 pubmed: 24845249 pmcid: 4076973
(2019) Guide to Professional Conduct and Ethics for Registered Medical Practitioners. 8th Edition
(1950) Declaration of Helsinki, Article 40.3 Bunreacht Na hEireann, the common law, European Convention for the Protection of Human Rights and Fundamental Freedoms, European Convention on Human
Health Service Executive (2019) National Quality Improvement Division. National Consent Policy – Quality Improvement Programmes. HSE. https://www.hse.ie/eng/about/who/qid/other-quality-improvement-programmes/consent/ . Accessed 20 April 2020
Wallace R, Greene E (2020) Survey of NCHDs in Ireland to assess their views and opinions in relation to participation in health research and the impact of new Irish data protection regulations. Ir J Med Sci 189:783–789. https://doi.org/10.1007/s11845-020-02185-8
doi: 10.1007/s11845-020-02185-8 pubmed: 32034653
Streamlining patient participation in health research biobanks. Patient Voice in Cancer Research. Wednesday, 9th October 2019, Cork. Available from: https://www.eventbrite.ie/e/streamlining-patient-participation-in-health-research-biobanks-tickets-71043873137#REPORT
Department of Health. Guidance on Information Principles for informed consent for the processing of personal data for health research. October 2018. Accessed 20 April 2020. Available from: https://www.hrb.ie/funding/gdpr-guidance-for-researchers/gdpr-and-health-research/
Mee B, Gaffney E, McGarrigle S et al (2016) Can a biobank network and supporting infrastructure enhance Ireland’s ability to attract pharmaceutical research and development and clinical trial opportunities? A pilot survey. J Biorepos Sci Appl Med 4:1–8. https://doi.org/10.2147/BSAM.S103837

Auteurs

Blanaid Mee (B)

Department of Histopathology, St James's Hospital, Dublin, Ireland. bmee@stjames.ie.

Mary Kirwan (M)

Department of General Practice, Royal College of Surgeons in Ireland, Dublin, Ireland.

Niamh Clarke (N)

Department of Surgery, School of Medicine, Faculty of Health Sciences, Trinity College Dublin, Dublin, Ireland.

Aoife Tanaka (A)

Department of Histopathology, St James's Hospital, Dublin, Ireland.
Biobank Ireland Trust, Dublin, Ireland.

Lino Manaloto (L)

School of Biotechnology, Faculty of Science and Health, Dublin City University, Dublin, Ireland.

Emma Halpin (E)

School of Biotechnology, Faculty of Science and Health, Dublin City University, Dublin, Ireland.

Una Gibbons (U)

Department of Histopathology, St James's Hospital, Dublin, Ireland.

Ann Cullen (A)

Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland.

Sarah McGarrigle (S)

Department of Surgery, School of Medicine, Faculty of Health Sciences, Trinity College Dublin, Dublin, Ireland.

Elisabeth M Connolly (EM)

Department of Surgery, St James's Hospital, Dublin, Ireland.

Kathleen Bennett (K)

Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

Eoin Gaffney (E)

Biobank Ireland Trust, Dublin, Ireland.

Ciaran Flanagan (C)

Biobank Ireland Trust, Dublin, Ireland.

Laura Tier (L)

Department of Histopathology, St James's Hospital, Dublin, Ireland.

Richard Flavin (R)

Department of Histopathology, St James's Hospital, Dublin, Ireland.

Noel G McElvaney (NG)

Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

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