Ocular Biometric Determinants of Anterior Chamber Angle Width in Chinese Americans: The Chinese American Eye Study.
Journal
American journal of ophthalmology
ISSN: 1879-1891
Titre abrégé: Am J Ophthalmol
Pays: United States
ID NLM: 0370500
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
17
02
2020
revised:
17
07
2020
accepted:
17
07
2020
pubmed:
31
7
2020
medline:
23
12
2020
entrez:
31
7
2020
Statut:
ppublish
Résumé
We sought to investigate anatomic mechanisms of angle narrowing by assessing ocular biometric determinants of anterior chamber angle width. Population-based cross-sectional study. Subjects ≥50 years of age from the Chinese American Eye Study underwent a comprehensive ocular examination, including anterior segment optical coherence tomography imaging and ultrasound A-scan. Independent variables, including anterior chamber depth (ACD), lens vault (LV), iris curvature (IC), anterior chamber width, lens thickness, vitreous cavity depth, and axial length, and dependent variables, including angle opening distance, were measured in 1 randomly selected eye per subject. Univariable and multivariable regression models with standardized regression coefficients (SRCs) and semipartial correlation coefficients squares (SPCC Two thousand two hundred twenty-five subjects (1433 women and 834 men) were included in the analysis. All biometric parameters except lens thickness differed between men and women (age-adjusted P < .001). In model 1A (R ACD, LV, and IC are the strongest determinants of angle width in Chinese Americans. Sex-related differences in angle width are explained by differences among biometric measurements. These results provide insights into anatomic mechanisms of angle narrowing and have important implications for quantitative assessments of angle closure eyes.
Identifiants
pubmed: 32730913
pii: S0002-9394(20)30388-3
doi: 10.1016/j.ajo.2020.07.030
pmc: PMC7686234
mid: NIHMS1616457
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
19-26Subventions
Organisme : NEI NIH HHS
ID : K23 EY029763
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY029220
Pays : United States
Organisme : NEI NIH HHS
ID : U10 EY017337
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001855
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Références
Invest Ophthalmol Vis Sci. 2012 May 31;53(6):3139-44
pubmed: 22531702
Ophthalmology. 2011 Mar;118(3):474-9
pubmed: 21035864
Prog Retin Eye Res. 2018 Sep;66:132-156
pubmed: 29635068
Am J Ophthalmol. 2019 Dec;208:273-280
pubmed: 31445003
PLoS One. 2018 Jul 23;13(7):e0199157
pubmed: 30036362
JAMA. 2014 May 14;311(18):1901-11
pubmed: 24825645
Ophthalmology. 2014 Nov;121(11):2081-90
pubmed: 24974815
Br J Ophthalmol. 2002 Feb;86(2):238-42
pubmed: 11815354
Ophthalmology. 2016 Dec;123(12):2519-2526
pubmed: 27726963
Ophthalmology. 2014 Aug;121(8):1566-71
pubmed: 24679835
Invest Ophthalmol Vis Sci. 2011 Nov 07;52(12):8672-9
pubmed: 21908580
PLoS Genet. 2014 Mar 06;10(3):e1004089
pubmed: 24603532
Curr Opin Ophthalmol. 2010 Mar;21(2):91-9
pubmed: 20051857
Invest Ophthalmol Vis Sci. 2014 Oct 21;55(11):7403-9
pubmed: 25335976
Arch Ophthalmol. 2000 Feb;118(2):257-63
pubmed: 10676792
Eye (Lond). 2011 Mar;25(3):261-7
pubmed: 21242985
Graefes Arch Clin Exp Ophthalmol. 2013 Apr;251(4):1205-11
pubmed: 23001586
Sci Rep. 2016 Mar 07;6:22931
pubmed: 26947903
Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5714-9
pubmed: 26313306
Ophthalmology. 2012 Feb;119(2):278-82
pubmed: 22118998
Ophthalmic Epidemiol. 2013 Dec;20(6):335-47
pubmed: 24044409
JAMA Ophthalmol. 2017 Jul 1;135(7):724-732
pubmed: 28520882
Ophthalmology. 2012 Jun;119(6):1134-42
pubmed: 22361313
Arch Ophthalmol. 2005 Apr;123(4):527-32
pubmed: 15824227
Br J Ophthalmol. 2011 Jan;95(1):46-50
pubmed: 20530187
Invest Ophthalmol Vis Sci. 2013 Mar 05;54(3):1650-5
pubmed: 23299476
Lancet. 2019 Apr 20;393(10181):1609-1618
pubmed: 30878226
Invest Ophthalmol Vis Sci. 2006 Jul;47(7):2782-8
pubmed: 16799014
Arch Ophthalmol. 2008 May;126(5):686-91
pubmed: 18474780
Am J Ophthalmol. 2019 Jul;203:37-45
pubmed: 30849350
Ophthalmology. 2010 Jan;117(1):11-7
pubmed: 19815290
Transl Vis Sci Technol. 2020 Mar 30;9(2):18
pubmed: 32818079
Ophthalmol Glaucoma. 2018 Nov-Dec;1(3):158-166
pubmed: 31025032
Ophthalmology. 2013 Jan;120(1):48-54
pubmed: 23009888
Am J Ophthalmol. 2014 Jan;157(1):32-38.e1
pubmed: 24210768
Asia Pac J Ophthalmol (Phila). 2019 Apr 25;:
pubmed: 31020820
Arch Ophthalmol. 2010 Oct;128(10):1321-7
pubmed: 20938002
Invest Ophthalmol Vis Sci. 2013 Apr 26;54(4):2977-84
pubmed: 23482467