Fetal Lymphoid Organ Immune Responses to Transient and Persistent Infection with Bovine Viral Diarrhea Virus.
Adaptive Immunity
Animals
Bovine Virus Diarrhea-Mucosal Disease
/ immunology
Cattle
Diarrhea Viruses, Bovine Viral
/ classification
Female
Fetus
/ immunology
Gene Expression Profiling
Immunity, Innate
Lymphoid Tissue
/ immunology
Pregnancy
Pregnancy Complications, Infectious
/ veterinary
Spleen
/ immunology
Thymus Gland
/ immunology
bovine viral diarrhea virus
fetus
immune response
thymus
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
28 07 2020
28 07 2020
Historique:
received:
05
06
2020
revised:
22
07
2020
accepted:
24
07
2020
entrez:
1
8
2020
pubmed:
1
8
2020
medline:
25
2
2021
Statut:
epublish
Résumé
Bovine Viral Diarrhea Virus (BVDV) fetal infections occur in two forms; persistent infection (PI) or transient infection (TI), depending on what stage of gestation the fetus is infected. Examination of lymphoid organs from both PI and TI fetuses reveals drastically different fetal responses, dependent upon the developmental stage of the fetal immune system. Total RNA was extracted from the thymuses and spleens of uninfected control, PI, and TI fetuses collected on day 190 of gestation to test the hypothesis that BVDV infection impairs the innate and adaptive immune response in the fetal thymus and spleen of both infection types. Transcripts of genes representing the innate immune response and adaptive immune response genes were assayed by Reverse Transcription quatitative PCR (RT-qPCR) (2
Identifiants
pubmed: 32731575
pii: v12080816
doi: 10.3390/v12080816
pmc: PMC7472107
pii:
doi:
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Références
Anim Health Res Rev. 2005 Jun;6(1):63-74
pubmed: 16164009
J Virol. 2004 Feb;78(4):1792-9
pubmed: 14747544
Cornell Vet. 1946 Jul;36:205-13
pubmed: 20995890
J Gen Virol. 2001 Aug;82(Pt 8):1893-1897
pubmed: 11457995
Vet J. 2014 Feb;199(2):201-9
pubmed: 24053990
Science. 1999 Dec 10;286(5447):2098-102
pubmed: 10617422
Cell Mol Immunol. 2010 Mar;7(2):89-93
pubmed: 20190822
Virus Res. 2012 Aug;167(2):329-36
pubmed: 22659490
Vet Rec. 1980 Jun 7;106(23):473-9
pubmed: 6255660
Science. 2010 Dec 17;330(6011):1695-9
pubmed: 21164017
Virology. 2000 Oct 10;276(1):70-82
pubmed: 11021996
Virus Res. 2006 Mar;116(1-2):69-77
pubmed: 16194578
Virus Res. 2013 May;173(2):260-9
pubmed: 23458997
Can J Comp Med. 1984 Apr;48(2):156-61
pubmed: 6326980
Viruses. 2017 Oct 21;9(10):
pubmed: 29065472
Clin Chem. 2009 Apr;55(4):611-22
pubmed: 19246619
Prev Vet Med. 2017 Feb 1;137(Pt A):77-92
pubmed: 28040270
Vet Clin North Am Food Anim Pract. 1995 Nov;11(3):447-76
pubmed: 8581857
Crit Rev Immunol. 2003;23(3):149-97
pubmed: 14584878
J Biol Chem. 2014 Aug 22;289(34):23568-81
pubmed: 25002588
J Gen Virol. 1987 Jul;68 ( Pt 7):1971-82
pubmed: 3037018
Vet Immunol Immunopathol. 2004 Aug;100(3-4):135-44
pubmed: 15207451
J Interferon Cytokine Res. 2009 Jan;29(1):23-35
pubmed: 19014339
Comp Immunol Microbiol Infect Dis. 2016 Dec;49:39-46
pubmed: 27865262
Biologicals. 2003 Jun;31(2):97-102
pubmed: 12770538
Vet Rec. 1984 Jun 2;114(22):535-6
pubmed: 6087539
Physiol Genomics. 2009 Feb 2;36(3):129-39
pubmed: 19018046
J Virol. 2006 Jan;80(2):900-11
pubmed: 16378992
Biologicals. 2013 Jan;41(1):39-51
pubmed: 22871358
Virus Res. 2008 Mar;132(1-2):49-58
pubmed: 18053605
Ann Rech Vet. 1987;18(2):157-66
pubmed: 3619343
Vet J. 2017 Feb;220:80-87
pubmed: 28190502
J Virol. 2002 Jan;76(2):923-7
pubmed: 11752182
Vet Pathol. 1988 May;25(3):231-6
pubmed: 3293305
Trends Immunol. 2018 Jun;39(6):503-514
pubmed: 29567327
J Gen Virol. 2017 Jan;98(1):2-3
pubmed: 28218572
Am J Vet Res. 1985 Apr;46(4):884-6
pubmed: 3893241
Annu Rev Anim Biosci. 2014 Feb;2:141-63
pubmed: 25384138
Sci Rep. 2015 Aug 03;5:12748
pubmed: 26235972
Anim Health Res Rev. 2015 Jun;16(1):15-26
pubmed: 26050568
Biol Reprod. 2020 Aug 21;103(3):560-571
pubmed: 32483591
Arch Virol. 2017 Nov;162(11):3473-3480
pubmed: 28795249
Virus Res. 2014 Apr;183:95-106
pubmed: 24530541
J Virol. 2006 Apr;80(8):3912-22
pubmed: 16571808
J Gen Virol. 2008 Oct;89(Pt 10):2501-2506
pubmed: 18796719
Adv Immunol. 1984;36:87-142
pubmed: 6209968
J Virol. 2007 Apr;81(7):3327-38
pubmed: 17215285
Can J Comp Med. 1978 Apr;42(2):239-43
pubmed: 208738
Vet Clin North Am Food Anim Pract. 1995 Nov;11(3):501-20
pubmed: 8581860
Am J Vet Res. 1971 Apr;32(4):533-44
pubmed: 5164965
Can J Comp Med. 1982 Oct;46(4):363-9
pubmed: 6293688
J Clin Immunol. 1987 Mar;7(2):81-97
pubmed: 2437143
Nat Rev Immunol. 2005 May;5(5):375-86
pubmed: 15864272
Virology. 2007 Sep 30;366(2):277-92
pubmed: 17531282
Adv Virus Res. 2015;93:47-160
pubmed: 26111586
J Virol. 2002 Sep;76(18):8979-88
pubmed: 12186882
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
Am J Reprod Immunol. 2013 Apr;69(4):346-58
pubmed: 23432802
Infect Immun. 1973 Jun;7(6):981-91
pubmed: 4123777