Julich-Brain: A 3D probabilistic atlas of the human brain's cytoarchitecture.


Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
21 08 2020
Historique:
received: 27 02 2020
accepted: 24 06 2020
pubmed: 1 8 2020
medline: 22 9 2020
entrez: 1 8 2020
Statut: ppublish

Résumé

Cytoarchitecture is a basic principle of microstructural brain parcellation. We introduce Julich-Brain, a three-dimensional atlas containing cytoarchitectonic maps of cortical areas and subcortical nuclei. The atlas is probabilistic, which enables it to account for variations between individual brains. Building such an atlas was highly data- and labor-intensive and required the development of nested, interdependent workflows for detecting borders between brain areas, data processing, provenance tracking, and flexible execution of processing chains to handle large amounts of data at different spatial scales. Full cortical coverage was achieved by the inclusion of gap maps to complement cortical maps. The atlas is dynamic and will be adapted as mapping progresses; it is openly available to support neuroimaging studies as well as modeling and simulation; and it is interoperable, enabling connection to other atlases and resources.

Identifiants

pubmed: 32732281
pii: science.abb4588
doi: 10.1126/science.abb4588
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

988-992

Informations de copyright

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Auteurs

Katrin Amunts (K)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany. k.amunts@fz-juelich.de h.mohlberg@fz-juelich.de.
C. and O. Vogt Institute for Brain Research, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Hartmut Mohlberg (H)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany. k.amunts@fz-juelich.de h.mohlberg@fz-juelich.de.

Sebastian Bludau (S)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.

Karl Zilles (K)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.

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Classifications MeSH