Malignant Phyllodes Tumor of the Breast With Metastasis to the Orbit: A Rare Case Report.


Journal

Ophthalmic plastic and reconstructive surgery
ISSN: 1537-2677
Titre abrégé: Ophthalmic Plast Reconstr Surg
Pays: United States
ID NLM: 8508431

Informations de publication

Date de publication:
Historique:
pubmed: 1 8 2020
medline: 13 4 2021
entrez: 1 8 2020
Statut: ppublish

Résumé

Phyllodes tumors are rare and account for 0.5% of all mammary neoplasms. They commonly present as lobulated breast tumors and have a variable clinical course. Histologically, phyllodes tumor is composed of 2 major elements: stromal element composed of spindle cells admixed with collagen and epithelial element in the form of epithelium lined cysts and clefts. Metastasis is rarely seen with phyllodes tumors. Sarcomatous component of phyllodes tumor metastasizes to lung, liver, adrenal, brain, and bones by hematogenous route. A thorough literature search did not reveal any report of orbital metastasis from malignant phyllodes tumor. Here, the authors describe a rare case of malignant phyllodes tumor of the breast with metastasis to the orbit in a 46-year-old female patient.

Identifiants

pubmed: 32732545
pii: 00002341-202101000-00032
doi: 10.1097/IOP.0000000000001693
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e5-e7

Informations de copyright

Copyright © 2020 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.

Déclaration de conflit d'intérêts

The authors have no financial or conflicts of interest to disclose.

Références

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Ramakant P, Chakravarthy S, Cherian JA, et al. Challenges in management of phyllodes tumors of the breast: a retrospective analysis of 150 patients. Indian J Cancer 2013;50:345–348.
Ramakant P, Selvamani, Therese MM, et al. Metastatic malignant phyllodes tumor of the breast: an aggressive disease-analysis of 7 cases. Indian J Surg Oncol 2015;6:363–369.
Asoglu O, Karanlik H, Barbaros U, et al. Malignant phyllode tumor metastatic to the duodenum. World J Gastroenterol 2006;12:1649–1651.
Serikawa M, Sasaki T, Kobayashi K, et al. [Malignant phyllodes tumor metastatic to the pancreas: a case report]. Nihon Shokakibyo Gakkai Zasshi 2012;109:795–803.
Garg N, Moorthy N, Agrawal SK, et al. Delayed cardiac metastasis from phyllodes breast tumor presenting as cardiogenic shock. Tex Heart Inst J 2011;38:441–444.
Suárez Roa Mde L, Ruiz Godoy Rivera LM, Vela Chávez T, et al. Breast malignant phyllodes tumour metastasising to soft tissues of oral cavity. Clin Transl Oncol 2007;9:258–261.
Ajenifuja OK, Kolomeyevskaya N, Habib F, et al. Phyllodes tumor of the breast metastasizing to the vulva. Case Rep Oncol Med 2015;2015:589547.
Durga G, Gandhi JS, Mehta A. Malignant phyllodes tumor metastatic to bilateral ovaries: a Krukenberg-like presentation. J Cancer Res Ther 2018;14:1138–1141.
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Auteurs

Vijitha S Vempuluru (VS)

Operation Eyesight Universal Institute for Eye Cancer and.

Dilip K Mishra (DK)

Ophthalmic Pathology Laboratory, LV Prasad Eye Institute, Hyderabad, India.

Swathi Kaliki (S)

Operation Eyesight Universal Institute for Eye Cancer and.

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