Use of Clozapine in the General Hospital.

Antipsychotic Agents / adverse effects Clozapine / adverse effects Hospitals, General Humans Psychiatry Referral and Consultation Schizophrenia, Treatment-Resistant
clozapine consultation-liaison psychiatry general hospital treatment-resistant schizophrenia

Journal

Psychopharmacology bulletin
ISSN: 2472-2448
Titre abrégé: Psychopharmacol Bull
Pays: United States
ID NLM: 0101123

Informations de publication

Date de publication:
23 07 2020
Historique:
entrez: 1 8 2020
pubmed: 1 8 2020
medline: 15 12 2021
Statut: ppublish

Résumé

Patients with treatment-resistant schizophrenia receiving clozapine therapy are at risk of potentially serious complications in the general hospital setting, due to the complex pharmacokinetic and pharmacodynamic profile of clozapine. We summarize common clinical challenges that face clinicians who care for clozapine patients in the general hospital, and make recommendations based on the available literature and clinical experience. Early collaborative management between consultation-liaison psychiatry and other clinical teams in the general hospital is paramount to improve clinical outcomes and avoid serious complications in this patient group.

Identifiants

PMID: 32733115 PMC: PMC7377545
pubmed: 32733115
pmc: PMC7377545

Substances chimiques

Antipsychotic Agents 0
Clozapine J60AR2IKIC

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

119-124

Informations de copyright

Copyright © 1964–2019 by MedWorks Media Inc, Los Angeles, CA All rights reserved. Printed in the United States.

Déclaration de conflit d'intérêts

Disclosure The author has no conflicts of interest to declare.

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Auteurs

Feras Ali Mustafa (FA)

Mustafa, MD, Department of Liaison Psychiatry, Northampton General Hospital, Northampton, United Kingdom.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Psychoanaleptiques › Tranquillisants › Neuroleptiques › Use of Clozapine in the General Hospital.
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérocycliques 3 noyaux › Dibenzazépines › Clozapine › Use of Clozapine in the General Hospital.
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Établissements de santé › Hôpitaux › Hôpitaux généraux › Use of Clozapine in the General Hospital.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Use of Clozapine in the General Hospital.
questionsmedicales.fr › Professions de santé › Médecine › Psychiatrie › Use of Clozapine in the General Hospital.
questionsmedicales.fr › Administration des services de santé › Organisation et administration › Pratique professionnelle › Orientation vers un spécialiste › Use of Clozapine in the General Hospital.
questionsmedicales.fr › Troubles mentaux › Schizophrénie et troubles avec traits psychotiques › Schizophrénie › Schizophrénie résistante au traitement › Use of Clozapine in the General Hospital.