Determinants of Bone Health in Older Adults.

The objective of this study was to determine the predictors of bone health in older adults. A total of 313 subjects older than 65 years (mean age 74.2±6.4 years, 70.6% female) were included in the study. Demographic characteristics of participants such as gait speed, handgrip strength, level of physical activity (using Rapid Assessment of Physical Activity-RAPA scale), vitamin D levels, T scores of femur neck (FN) and lumbar spine (LS) were recorded. Based on FN, 40.7% of participants had normal T scores whereas 46.2% and 13.1% of them were osteopenic and osteoporotic, respectively. FN was correlated with age (r:-0.184, p<0.001), BMI (r:0.269, p<0.001), and handgrip strength (r:0.149, p:0.009) in addition to the aerobic subscale of RAPA (RAPA-aerobic) (r:-0.133, p:0.02). Similarly, the LS was correlated with female gender (r:-0.207, p<0.001), age (r:0.136, p:0.016), body mass index (BMI) (r:0.246, p<0.001) and handgrip strength (r:0.217, p<0.001). The predictors of bone health were decided upon using multiple logistic regression analysis. The deterministic model consisted of age, gender, BMI, height, weight, handgrip strength, gait speed, RAPA-aerobic and vitamin D. For LS dependent variable, the overall model was significant (F:10.149, p<0.001). However, only two variables were significant predictors in the model ie. weight (β:0.389, p<0.001) and handgrip strength (β=0.186, p<0.001). Similarly for independent variable of FN, the overall model was significant (F:6.525, p<0.001) and only two variables were significant predictors: weight (β:0.371, p<0.001) and RAPA-Aerobic (β:0.148, p:0.009). Lower levels of body weight, participation in aerobic activity and handgrip strength might be risk factors for deterioration of bone health in older adults. Bu çalışmada amaç, yaşlı bireylerde kemik sağlığını belirleyen faktörleri saptamaktır. FN’e göre katılımcıların %40,7’si normal T skoru düzeylerine sahipken; %46,2’si osteopenik ve %13,1’i osteoporotikti. FN, yaş (r:-0.184, p<0.001), VKİ (r:0.269, p<0.001) ve kavrama kuvvetine (r:0.149, p:0.009) ek olarak FEHD’nin aerobik alt skalası (FEHD-aerobik) (r:-0.133, p:0.02) ile ilişkiliydi. Benzer şekilde LS, kadın cinsiyet (r:-0.207, p<0.001), yaş (r:0.136, p:0.016), vücut kitle indeksi (VKİ) (r:0.246, p<0.001) ve kavrama kuvveti (r:0.217, p<0.001) ile ilişkiliydi. Kemik sağlığının belirleyicileri çoklu lojistik regresyon analizi kullanılarak kararlaştırıldı. Belirleyici model içerisinde yaş, cinsiyet, VKİ, boy, kilo, kavrama kuvveti, yürüyüş hızı, FEHD-aerobik ve vitamin D yer aldı. LS bağımsız değişkeni için, model anlamlıydı (F:10.149, p<0.001); ancak, modelde yer alan değişkenlerden yalnızca kilo (β:0.389, p<0.001) ve kavrama kuvveti (β:0.186, p<0.001) anlamlı belirleyiciydi. Benzer şekilde FN bağımsız değişkeni için, model anlamlıydı (F:6.525, p<0.001) ve yalnızca iki değişken anlamlı belirleyiciydi: kilo (β:0.371, p<0.001) ve FEHD-aerobik (β:0.148, p:0.009). Düşük vücut ağırlığı, aerobik aktivite katılım düzeyi ve kavrama kuvveti gibi faktörler yaşlı bireylerde kemik sağlığının bozulması açısından risk faktörü olabilir.

Informations de copyright

Copyright Istanbul Medeniyet University Faculty of Medicine.

Déclaration de conflit d'intérêts

Conflict of interest: The authors declare that they have no conflict of interest.