Sars-CoV-2 in pregnancy: Why is it better than expected?
Immunology
Inflammation
Pregnancy
Sars-CoV-2
Journal
European journal of obstetrics, gynecology, and reproductive biology
ISSN: 1872-7654
Titre abrégé: Eur J Obstet Gynecol Reprod Biol
Pays: Ireland
ID NLM: 0375672
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
27
06
2020
revised:
09
07
2020
accepted:
11
07
2020
pubmed:
3
8
2020
medline:
12
9
2020
entrez:
3
8
2020
Statut:
ppublish
Résumé
Since the outbreak of Coronavirus disease in December 2019, information specific to pregnancy remains limited and controversial. Based on data from previous reports, it has been noticed that contrary to prior pandemics such as SARS, MERS and H1N1 and although pregnancy is usually considered as a condition of high susceptibility to viral infections, new SARS-CoV2 infection seems to have a more benign clinical course when affecting pregnant women. We speculate that during pregnancy the physiological "silencing" of the Th1 pro-inflammatory response may blunt the cytokines storm which is thought to play a key-role in the pathogenesis of the severe complications of Covid-19.
Identifiants
pubmed: 32739606
pii: S0301-2115(20)30467-X
doi: 10.1016/j.ejogrb.2020.07.025
pmc: PMC7378463
pii:
doi:
Substances chimiques
Cytokines
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
476-478Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None to declare
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