Role of autobiographical memory in the impact of MBCT on dysfunctional attitudes, depressive symptoms and anxiety in bipolar I patients.

Autobiographical memory Bipolar disorder Cognitive reactivity Dysfunctional attitudes Mindfulness-based cognitive therapy

Journal

Journal of affective disorders
ISSN: 1573-2517
Titre abrégé: J Affect Disord
Pays: Netherlands
ID NLM: 7906073

Informations de publication

Date de publication:
01 11 2020
Historique:
received: 19 02 2020
revised: 22 05 2020
accepted: 05 07 2020
pubmed: 3 8 2020
medline: 16 2 2021
entrez: 3 8 2020
Statut: ppublish

Résumé

The literature suggests that cognitive reactivity in bipolar patients can increase relapse vulnerability, is enhanced by depressive mood and dysfunctional attitudes, and could be improved with MBCT. Autobiographical memory (AM) could be involved in cognitive reactivity, and improved with MBCT training. This study aims to investigate the effect of MBCT for bipolar patients on depressive and anxious symptoms, dysfunctional attitudes and AM, and the predictive versus mediating role of AM in the impact of MBCT on clinical symptoms. Sixty-two outpatients diagnosed with bipolar I disorder were assigned to MBCT and were compared to 37 bipolar patients on a waiting list. Affective symptoms and dysfunctional attitudes were explored using self-report inventories (BDI, BAI, DAS) and AM was assessed using the Autobiographical Memory Test. Patients receiving MBCT demonstrated significantly decreased depressive symptoms, dysfunctional attitudes, overgeneral memories and omissions, and increased specific memories. General AM and omissions at baseline respectively predicted lower anxiety and dysfunctional attitudes improvement following therapy, but the improvement of AM did not explain the impact of MBCT on depression and dysfunctional attitudes improvement. Further studies should consider patients' therapeutic adherence and mechanisms involved in MBCT in order to better apprehend how MBCT may reduce dysfunctional attitudes and improve AM in bipolar patients. Results are consistent with the hypothesis that MBCT reduces cognitive reactivity and AM impairment in bipolar disorders. Findings suggest that AM training prior to MBCT may influence MBCT efficacy, but that MBCT efficacy on AM and clinical symptoms are non-related phenomena.

Sections du résumé

BACKGROUND
The literature suggests that cognitive reactivity in bipolar patients can increase relapse vulnerability, is enhanced by depressive mood and dysfunctional attitudes, and could be improved with MBCT. Autobiographical memory (AM) could be involved in cognitive reactivity, and improved with MBCT training. This study aims to investigate the effect of MBCT for bipolar patients on depressive and anxious symptoms, dysfunctional attitudes and AM, and the predictive versus mediating role of AM in the impact of MBCT on clinical symptoms.
METHODS
Sixty-two outpatients diagnosed with bipolar I disorder were assigned to MBCT and were compared to 37 bipolar patients on a waiting list. Affective symptoms and dysfunctional attitudes were explored using self-report inventories (BDI, BAI, DAS) and AM was assessed using the Autobiographical Memory Test.
RESULTS
Patients receiving MBCT demonstrated significantly decreased depressive symptoms, dysfunctional attitudes, overgeneral memories and omissions, and increased specific memories. General AM and omissions at baseline respectively predicted lower anxiety and dysfunctional attitudes improvement following therapy, but the improvement of AM did not explain the impact of MBCT on depression and dysfunctional attitudes improvement.
LIMITS
Further studies should consider patients' therapeutic adherence and mechanisms involved in MBCT in order to better apprehend how MBCT may reduce dysfunctional attitudes and improve AM in bipolar patients.
CONCLUSION
Results are consistent with the hypothesis that MBCT reduces cognitive reactivity and AM impairment in bipolar disorders. Findings suggest that AM training prior to MBCT may influence MBCT efficacy, but that MBCT efficacy on AM and clinical symptoms are non-related phenomena.

Identifiants

pubmed: 32739709
pii: S0165-0327(20)32517-9
doi: 10.1016/j.jad.2020.07.072
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

907-913

Informations de copyright

Copyright © 2020. Published by Elsevier B.V.

Auteurs

Aurélie Docteur (A)

GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, CMME, F-75014 Paris, France.

Christine Mirabel-Sarron (C)

GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, CMME, F-75014 Paris, France.

Héline Kaya Lefèvre (H)

GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, CMME, F-75014 Paris, France; Université de Paris, LPPS, F-92100 Boulogne-Billancourt, France. Electronic address: h.kaya_lefevre@ghu-paris.fr.

Loretta Sala (L)

GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, CMME, F-75014 Paris, France.

Mathilde Husky (M)

Laboratoire de Psychologie EA4139, Université de Bordeaux, Bordeaux, France.

Joel Swendsen (J)

INCIA, UMR 5287, CNRS/Université de Bordeaux, Bordeaux, France.

Philip Gorwood (P)

GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, CMME, F-75014 Paris, France; Université de Paris, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, F-75014 Paris, France.

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