Diabetes Insipidus: An Update.

Diabetes Insipidus / diagnosis Diabetes Insipidus, Nephrogenic / diagnosis Diabetes Mellitus / diagnosis Diagnosis, Differential Diagnostic Techniques, Endocrine / standards Humans Syndrome
Diabetes insipidus Polyuria polydipsia syndrome Primary polydipsia

Journal

Endocrinology and metabolism clinics of North America
ISSN: 1558-4410
Titre abrégé: Endocrinol Metab Clin North Am
Pays: United States
ID NLM: 8800104

Informations de publication

Date de publication:
09 2020
Historique:
entrez: 4 8 2020
pubmed: 4 8 2020
medline: 22 6 2021
Statut: ppublish

Résumé

The differential diagnosis of diabetes insipidus involves the distinction between central or nephrogenic diabetes insipidus and primary polydipsia. Differentiation is important because treatment strategies vary; the wrong treatment can be dangerous. Reliable differentiation is difficult especially in patients with primary polydipsia or partial forms of diabetes insipidus. New diagnostic algorithms are based on the measurement of copeptin after osmotic stimulation by hypertonic saline infusion or after nonosmotic stimulation by arginine and have a higher diagnostic accuracy than the water deprivation test. Treatment involves correcting preexisting water deficits, but is different for central diabetes insipidus, nephrogenic diabetes insipidus, and primary polydipsia.

Identifiants

DOI: 10.1016/j.ecl.2020.05.012 PMID: 32741486
pubmed: 32741486
pii: S0889-8529(20)30039-6
doi: 10.1016/j.ecl.2020.05.012
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

517-531

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Competing interests M. Christ-Crain received speaking honoraria from Thermo Fisher AG, the manufacturer of the copeptin assay.

Auteurs

Julie Refardt (J)

Division of Endocrinology, Diabetes and Metabolism, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Endocrinology, University Hospital Basel, University of Basel, Petersgraben 4, Basel 4031, Switzerland.

Bettina Winzeler (B)

Division of Endocrinology, Diabetes and Metabolism, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Endocrinology, University Hospital Basel, University of Basel, Petersgraben 4, Basel 4031, Switzerland.

Mirjam Christ-Crain (M)

Division of Endocrinology, Diabetes and Metabolism, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Endocrinology, University Hospital Basel, University of Basel, Petersgraben 4, Basel 4031, Switzerland. Electronic address: mirjam.christ@usb.ch.

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Classifications MeSH

questionsmedicales.fr › Maladies endocriniennes › Maladies de l'hypophyse › Diabète insipide › Diabetes Insipidus: An Update.
questionsmedicales.fr › Maladies urogénitales › Maladies urologiques › Maladies du rein › Diabète insipide néphrogénique › Diabetes Insipidus: An Update.
questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabetes Insipidus: An Update.
questionsmedicales.fr › Diagnostic › Diagnostic différentiel › Diabetes Insipidus: An Update.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic endocrinien › Diabetes Insipidus: An Update.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Diabetes Insipidus: An Update.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Maladie › Syndrome › Diabetes Insipidus: An Update.