Multiple Plantar Poromas in a Stem Cell Transplant Patient.
acute myeloid leukemia
chronic immunosuppression
eccrine poroma
graft versus host disease
lymphoproliferative neoplasm
multiple poromas
poromatosis
stem cell transplantation
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
22 Jun 2020
22 Jun 2020
Historique:
entrez:
4
8
2020
pubmed:
4
8
2020
medline:
4
8
2020
Statut:
epublish
Résumé
Poromatosis, or the formation of multiple eccrine poromas, is associated with chronic immunosuppression, lymphoproliferative neoplasms, and stem cell transplantation, though the etiology and clinical significance remain poorly understood. Eccrine poromas are asymptomatic, may appear years after treatment, and overlap morphologically with other diagnoses, particularly human papillomavirus-associated verrucae, to which immunosuppressed patients may be predisposed and commonly occur in similar sites. We report a 47-year-old female on chronic immunosuppression who developed multiple plantar eccrine poromas three years after achieving acute myeloid leukemia (AML) remission following treatment with chemotherapy, total body irradiation, and allogenic stem cell transplantation. We propose that early recognition, timely treatment, and regular follow-up skin examinations are necessary in the setting of multiple poromas to reduce the risk of malignancy and avoid delays in diagnosis.
Identifiants
pubmed: 32742823
doi: 10.7759/cureus.8773
pmc: PMC7384454
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e8773Informations de copyright
Copyright © 2020, Marsh et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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