Trends and associated characteristics for Chagas disease among women of reproductive age in the United States, 2002 to 2017.
Chagas disease
Ethnic/racial disparities
HCUP
Neglected disease
Reproductive health
United States
Journal
Parasite epidemiology and control
ISSN: 2405-6731
Titre abrégé: Parasite Epidemiol Control
Pays: Netherlands
ID NLM: 101687137
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
26
03
2020
revised:
14
07
2020
accepted:
15
07
2020
entrez:
4
8
2020
pubmed:
4
8
2020
medline:
4
8
2020
Statut:
epublish
Résumé
American trypanosomiasis, commonly referred to as Chagas disease, is caused by a single cell protozoan known as We analyzed admissions data including socio-demographic and hospital characteristics for inpatient hospitalization for women of reproductive age (15-49 years) in the US from 2002 through 2017. We employed Joinpoint regression analysis to determine trends in the prevalence of Chagas disease over this period. A total of 487 hospitalizations of Chagas disease were identified, corresponding to 3.7 per million hospitalizations over the study period. The rate statistically increased from 1.6 per million in 2002 to 7.6 per million hospitalizations in 2017. Chagas was most prevalent among older women, Hispanics and those in the highest zip income bracket. The in-hospital mortality rate was about 10 times greater among women with Chagas compared to those without the condition (3.1% versus 0.3%), and the condition tended to be clustered in women treated at large, urban teaching hospitals in the Northeastern region of the US. Chagas disease diagnosis appears to be increasing among hospitalized women of reproductive age in the US with a 10-fold elevated risk of mortality.
Sections du résumé
BACKGROUND
BACKGROUND
American trypanosomiasis, commonly referred to as Chagas disease, is caused by a single cell protozoan known as
METHODS
METHODS
We analyzed admissions data including socio-demographic and hospital characteristics for inpatient hospitalization for women of reproductive age (15-49 years) in the US from 2002 through 2017. We employed Joinpoint regression analysis to determine trends in the prevalence of Chagas disease over this period.
RESULTS
RESULTS
A total of 487 hospitalizations of Chagas disease were identified, corresponding to 3.7 per million hospitalizations over the study period. The rate statistically increased from 1.6 per million in 2002 to 7.6 per million hospitalizations in 2017. Chagas was most prevalent among older women, Hispanics and those in the highest zip income bracket. The in-hospital mortality rate was about 10 times greater among women with Chagas compared to those without the condition (3.1% versus 0.3%), and the condition tended to be clustered in women treated at large, urban teaching hospitals in the Northeastern region of the US.
CONCLUSION
CONCLUSIONS
Chagas disease diagnosis appears to be increasing among hospitalized women of reproductive age in the US with a 10-fold elevated risk of mortality.
Identifiants
pubmed: 32743081
doi: 10.1016/j.parepi.2020.e00167
pii: S2405-6731(20)30036-2
pii: e00167
pmc: PMC7388767
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e00167Informations de copyright
© 2020 The Authors. Published by Elsevier Ltd on behalf of World Federation of Parasitologists.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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