Syndrome of inappropriate antidiuretic hormone secretion as a side effect of chemotherapy for testicular cancer: A case report.
chemotherapy
hyponatremia
renal salt wasting syndrome
syndrome of inappropriate antidiuretic hormone secretion
testicular cancer
Journal
IJU case reports
ISSN: 2577-171X
Titre abrégé: IJU Case Rep
Pays: Australia
ID NLM: 101764958
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
02
07
2019
accepted:
18
09
2019
entrez:
4
8
2020
pubmed:
4
8
2020
medline:
4
8
2020
Statut:
epublish
Résumé
Inappropriate antidiuretic hormone secretion syndrome can be a serious adverse event of cisplatin-based chemotherapy. Cisplatin had to be changed to other drugs or chemotherapy completely discontinued in earlier reported cases. Three cycles of bleomycin, etoposide, and cisplatin chemotherapy were planned for a 40-year-old man with a diagnosis of lymph node recurrence of testicular cancer. On day 9, he suffered from vomiting and mental disturbance. Severe hyponatremia (110 mEq/L) with low plasma osmolality led to a diagnosis of a syndrome of inappropriate antidiuretic hormone secretion, and infusions of hypertonic saline and salt intake were prescribed. Second and third courses of bleomycin, etoposide, and cisplatin chemotherapy could then be given with careful electrolyte management. Continuation of cisplatin administration with precise electrolyte adjustment can be a treatment option in regimens where cisplatin is essential for achieving optimal antitumor efficacy.
Identifiants
pubmed: 32743452
doi: 10.1002/iju5.12122
pii: IJU512122
pmc: PMC7292171
doi:
Types de publication
Case Reports
Langues
eng
Pagination
327-329Informations de copyright
© 2019 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Urological Association.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Am J Med Sci. 2003 Jul;326(1):25-30
pubmed: 12861122
Pediatr Blood Cancer. 2013 Apr;60(4):587-92
pubmed: 22976789
Am J Kidney Dis. 2008 Jul;52(1):144-53
pubmed: 18468754
Support Care Cancer. 2007 Dec;15(12):1341-7
pubmed: 17701059
Br J Clin Pharmacol. 2017 Aug;83(8):1801-1807
pubmed: 28168757
Hinyokika Kiyo. 2012 Feb;58(2):97-100
pubmed: 22450837
Gan To Kagaku Ryoho. 2010 Oct;37(10):1945-8
pubmed: 20948261
Hinyokika Kiyo. 2016 Jul;62(7):361-6
pubmed: 27569354
Urol Case Rep. 2017 Mar 01;12:17-19
pubmed: 28271051
BMJ Case Rep. 2010;2010:
pubmed: 22242071
Am J Med. 1957 Oct;23(4):529-42
pubmed: 13469824
Hinyokika Kiyo. 2012 Aug;58(8):425-9
pubmed: 23052267
J Clin Pathol. 2002 Dec;55(12):893-6
pubmed: 12461050
J Intern Med. 1995 Aug;238(2):97-110
pubmed: 7629492
Support Care Cancer. 2000 May;8(3):192-7
pubmed: 10789959
N Engl J Med. 2007 May 17;356(20):2064-72
pubmed: 17507705