Frequencies and clinical associations of myositis-related antibodies in The Netherlands: A one-year survey of all Dutch patients.

Diagnostic parameters Idiopathic inflammatory myopathies Multiplex assay Myositis Validation

Journal

Journal of translational autoimmunity
ISSN: 2589-9090
Titre abrégé: J Transl Autoimmun
Pays: Netherlands
ID NLM: 101759413

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 31 05 2019
revised: 25 07 2019
accepted: 29 07 2019
entrez: 4 8 2020
pubmed: 4 8 2020
medline: 4 8 2020
Statut: epublish

Résumé

Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of connective tissue diseases, collectively known as myositis. Diagnosis of IIM is challenging while timely recognition of an IIM is of utter importance considering treatment options and otherwise irreversible (severe) long-term clinical complications. With the EULAR/ACR classification criteria (2017) considerable advancement has been made in the diagnostic workup of IIM. While these criteria take into account clinical parameters as well as presence of one autoantibody, anti-Jo-1, several autoantibodies are associated with IIM and are currently evaluated to be incorporated into classification criteria. As individual antibodies occur at low frequency, the development of line blots allowing multiplex antibody analysis has improved laboratory diagnostics for IIM. The Euroline myositis line-blot assay (Euroimmun) allows screening and semi-quantitative measurement for 15 autoantibodies,

Identifiants

pubmed: 32743501
doi: 10.1016/j.jtauto.2019.100013
pii: S2589-9090(19)30013-9
pii: 100013
pmc: PMC7388388
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100013

Informations de copyright

© 2019 The Authors.

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Auteurs

Anouk C M Platteel (ACM)

St. Antonius Hospital, Department of Medical Microbiology and Immunology, Nieuwegein, the Netherlands.

Brigitte A Wevers (BA)

Sanquin Diagnostic Services, Amsterdam, the Netherlands.
Atalmedial, Medical Diagnostic Center, Amsterdam, the Netherlands.
Amsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands.

Johan Lim (J)

Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Department of Neurology, Amsterdam, the Netherlands.

Jaap A Bakker (JA)

Leiden University Medical Center, Department of Clinical Chemistry and Laboratory Medicine, Leiden, the Netherlands.

Hetty J Bontkes (HJ)

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Clinical Chemistry, Amsterdam, the Netherlands.

Joyce Curvers (J)

Catharina Hospital Eindhoven, Clinical Laboratory, Eindhoven, the Netherlands.

Jan Damoiseaux (J)

Maastricht University Medical Center, Central Diagnostic Laboratory, Maastricht, the Netherlands.

Michiel Heron (M)

Elisabeth-TweeSteden Hospital, Department of Medical Microbiology and Immunology, Tilburg, the Netherlands.

Gijs de Kort (G)

LabWest, Den Haag, the Netherlands.

Maarten Limper (M)

University Medical Center Utrecht, Department of Rheumatology and Clinical Immunology, Utrecht, the Netherlands.

Ellen G van Lochem (EG)

Rijnstate Hospital, Department of Microbiology and Immunology, Arnhem, the Netherlands.

A H Leontine Mulder (AHL)

Medlon, Medical Diagnostics, Enschede, the Netherlands.

Christiaan G J Saris (CGJ)

Radboud University Medical Center, Donders Institute for Brain Cognition and Behaviour, Department of Neurology, Nijmegen, the Netherlands.

Hester van der Valk (H)

University Medical Center Groningen, Department of Rheumatology and Clinical Immunology, Groningen, the Netherlands.

Anneke J van der Kooi (AJ)

Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Department of Neurology, Amsterdam, the Netherlands.

Ester M M van Leeuwen (EMM)

Amsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands.

Marcel Veltkamp (M)

St Antonius Hospital, Interstitial Lung Diseases Center of Excellence, Department of Pulmonology, Nieuwegein, the Netherlands.
Division of Heart&Lungs, University Medical Center, Utrecht, the Netherlands.

Marco W J Schreurs (MWJ)

Erasmus MC University Medical Centre Rotterdam, Department of Immunology, Rotterdam, the Netherlands.

Bob Meek (B)

St. Antonius Hospital, Department of Medical Microbiology and Immunology, Nieuwegein, the Netherlands.

Dörte Hamann (D)

Sanquin Diagnostic Services, Amsterdam, the Netherlands.

Classifications MeSH