The Discovery of SWI/SNF Chromatin Remodeling Activity as a Novel and Targetable Dependency in Uveal Melanoma.
Journal
Molecular cancer therapeutics
ISSN: 1538-8514
Titre abrégé: Mol Cancer Ther
Pays: United States
ID NLM: 101132535
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
23
10
2019
revised:
15
11
2019
accepted:
21
07
2020
pubmed:
5
8
2020
medline:
7
8
2021
entrez:
5
8
2020
Statut:
ppublish
Résumé
Uveal melanoma is a rare and aggressive cancer that originates in the eye. Currently, there are no approved targeted therapies and very few effective treatments for this cancer. Although activating mutations in the G protein alpha subunits,
Identifiants
pubmed: 32747420
pii: 1535-7163.MCT-19-1013
doi: 10.1158/1535-7163.MCT-19-1013
doi:
Substances chimiques
Chromatin
0
Chromosomal Proteins, Non-Histone
0
SWI-SNF-B chromatin-remodeling complex
0
Transcription Factors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2186-2195Informations de copyright
©2020 American Association for Cancer Research.