A review of the costs of delivering maternal immunisation during pregnancy.
Costs
Economics
Immunisation
Maternal
Pregnancy
Vaccination
Journal
Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899
Informations de publication
Date de publication:
11 09 2020
11 09 2020
Historique:
received:
03
03
2020
revised:
19
06
2020
accepted:
22
07
2020
pubmed:
6
8
2020
medline:
28
4
2021
entrez:
6
8
2020
Statut:
ppublish
Résumé
Routine maternal immunisation against influenza and pertussis are recommended by the WHO to protect mother and child, and new vaccines are under development. Introducing maternal vaccines into national programmes requires an understanding of vaccine delivery costs - particularly in low resource settings. We searched Medline, Embase, Econlit, and Global Health for studies reporting costs of delivering vaccination during pregnancy but excluded studies that did not separate the vaccine purchase price. Extracted costs were inflated and converted to 2018 US dollars. Sixteen studies were included, of which two used primary data to estimate vaccine delivery costs. Costs per dose ranged from $0.55 to $0.64 in low-income countries, from $1.25 to $6.55 for middle-income countries, and from $5.76 to $39.87 in high-income countries. More research is needed on the costs of delivering maternal immunisation during pregnancy, and of integrating vaccine delivery into existing programmes of antenatal care especially in low and middle-income countries.
Sections du résumé
BACKGROUND
Routine maternal immunisation against influenza and pertussis are recommended by the WHO to protect mother and child, and new vaccines are under development. Introducing maternal vaccines into national programmes requires an understanding of vaccine delivery costs - particularly in low resource settings.
METHODS
We searched Medline, Embase, Econlit, and Global Health for studies reporting costs of delivering vaccination during pregnancy but excluded studies that did not separate the vaccine purchase price. Extracted costs were inflated and converted to 2018 US dollars.
RESULTS
Sixteen studies were included, of which two used primary data to estimate vaccine delivery costs. Costs per dose ranged from $0.55 to $0.64 in low-income countries, from $1.25 to $6.55 for middle-income countries, and from $5.76 to $39.87 in high-income countries.
CONCLUSIONS
More research is needed on the costs of delivering maternal immunisation during pregnancy, and of integrating vaccine delivery into existing programmes of antenatal care especially in low and middle-income countries.
Identifiants
pubmed: 32753292
pii: S0264-410X(20)30981-6
doi: 10.1016/j.vaccine.2020.07.050
pmc: PMC7482437
pii:
doi:
Substances chimiques
Influenza Vaccines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
6199-6204Subventions
Organisme : World Health Organization
ID : 001
Pays : International
Informations de copyright
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
Pediatrics. 2013 Jun;131(6):e1748-56
pubmed: 23713104
Vaccine. 2014 Apr 7;32(17):1954-63
pubmed: 24530145
Vaccine. 2017 Oct 27;35(45):6238-6247
pubmed: 28951085
Soc Sci Med. 1991;33(2):185-92
pubmed: 1909462
Clin Infect Dis. 2014 Aug 15;59(4):560-8
pubmed: 24799324
Vaccine. 2010 Mar 11;28(12):2370-84
pubmed: 20096762
Am J Epidemiol. 2016 Jun 15;183(12):1159-70
pubmed: 27188951
Can J Public Health. 2011 Nov-Dec;102(6):445-50
pubmed: 22164556
J Infect. 2016 Jul;73(1):28-37
pubmed: 27108802
Lancet Infect Dis. 2017 Jul;17(7):e197-e208
pubmed: 28433705
Vaccine. 2015 May 5;33(19):2213-2220
pubmed: 25825331
Vaccine. 2010 Dec 10;29(1):115-22
pubmed: 21055501
Hum Vaccin Immunother. 2016 Sep;12(9):2269-77
pubmed: 27184622
Vaccine X. 2019 Jul 15;2:100034
pubmed: 31428741
Vaccine. 2018 Nov 12;36(46):7033-7042
pubmed: 30293765
Wkly Epidemiol Rec. 2012 Nov 23;87(47):461-76
pubmed: 23210147
Vaccine. 2016 Jun 8;34(27):3149-3155
pubmed: 27161997
PLoS One. 2017 Dec 27;12(12):e0190006
pubmed: 29281710
Hum Vaccin Immunother. 2016 Aug 2;12(8):2003-2009
pubmed: 26900799
Lancet Infect Dis. 2017 Jul;17(7):e223-e234
pubmed: 28433702
Lancet Infect Dis. 2017 Jul;17(7):e209-e222
pubmed: 28433704
N Engl J Med. 2008 Oct 9;359(15):1555-64
pubmed: 18799552
N Engl J Med. 2017 Mar 30;376(13):1256-1267
pubmed: 28355514
Vaccine. 2016 Mar 18;34(13):1531-1539
pubmed: 26899375