Neuroendocrine Carcinoma of Uterine Cervix: Stereotactic Radiotherapy for Brain Metastasis and Stereotactic Body Radiotherapy for Renal and Pancreatic Metastases.

brain chemotherapy metastasis neuroendocrine carcinoma pancreatic renal stereotactic body radiotherapy stereotactic radiosurgery stereotactic radiotherapy uterine cervix

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
27 Jun 2020
Historique:
entrez: 6 8 2020
pubmed: 6 8 2020
medline: 6 8 2020
Statut: epublish

Résumé

A case of cervical neuroendocrine carcinoma (NEC) of the uterine cervix (NECUC) was presented. After total hysterectomy with bilateral salpingo-oophorectomy and adjuvant chemotherapy, a left renal tumor and a pancreatic lesion developed and were both diagnosed on pathological examination as metastases from NEC. In addition, a brainstem metastasis causing neurologic signs developed. The brain lesion was treated by stereotactic radiotherapy (SRT) and the renal and pancreatic lesions by stereotactic body radiotherapy (SBRT). Despite control of the renal and pancreatic lesions, multiple small lung metastases developed later. Recurrence and newly developed brain metastases were treated by repeat stereotactic radiosurgery (SRS)/SRT successfully. Chemotherapy was continued and controlled the lung metastases until three and a half years after the initial operation of the uterus.

Identifiants

pubmed: 32754406
doi: 10.7759/cureus.8869
pmc: PMC7386082
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e8869

Informations de copyright

Copyright © 2020, Mori et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Yoshimasa Mori (Y)

Radiation Oncology and Neurological Surgery, Shin-Yurigaoka General Hospital, Kawasaki, JPN.
Radiology and Radiation Oncology, Aichi Medical University, Nagakute, JPN.
Neurological Surgery, Ookuma Hospital, Nagoya, JPN.
Neurological Surgery, Aoyama General Hospital, Toyokawa, JPN.

Yoshihisa Kida (Y)

Gamma Knife Center, Ookuma Hospital, Nagoya, JPN.

Yasuhiro Matsushita (Y)

Neurological Surgery, Gamma Knife Center, Ookuma Hospital, Nagoya, JPN.

Shinichiro Mizumatsu (S)

Neurological Surgery, CyberKnife Center, Aoyama General Hospital, Toyokawa, JPN.

Manabu Hatano (M)

Neurological Surgery, Radiosurgery, CyberKnife Center, Aoyama General Hospital, Toyokawa, JPN.

Noriko Morita (N)

Gynecology, Aichi Medical University, Nagakute, JPN.

Toyonori Tsuzuki (T)

Surgical Pathology, Aichi Medical University, Nagakute, JPN.

Classifications MeSH