PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20.


Journal

Molecular biology of the cell
ISSN: 1939-4586
Titre abrégé: Mol Biol Cell
Pays: United States
ID NLM: 9201390

Informations de publication

Date de publication:
01 10 2020
Historique:
pubmed: 7 8 2020
medline: 8 6 2021
entrez: 7 8 2020
Statut: ppublish

Résumé

Ubiquitin-dependent proteolysis of cyclin B and securin initiates sister chromatid segregation and anaphase. The anaphase-promoting complex/cyclosome and its coactivator CDC20 (APC/C

Identifiants

pubmed: 32755477
doi: 10.1091/mbc.E20-04-0252
pmc: PMC7851957
doi:

Substances chimiques

Cdc20 Proteins 0
Cyclin B 0
Receptors, Neuropeptide Y 0
CDC20 protein, human 156288-95-8
neuropeptide Y4 receptor 55F8T1GN3X

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2315-2330

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K006703/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M00354X/1
Pays : United Kingdom
Organisme : Cancer Research UK
ID : C20079/A15940
Pays : United Kingdom

Commentaires et corrections

Type : ErratumIn

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Auteurs

James Bancroft (J)

Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.

James Holder (J)

Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

Zoë Geraghty (Z)

Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.

Tatiana Alfonso-Pérez (T)

Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

Daniel Murphy (D)

Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.

Francis A Barr (FA)

Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

Ulrike Gruneberg (U)

Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.

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Classifications MeSH