Farnesyl glycosides and one new triterpenoid saponin from the roots of Lecaniodiscus cupanioides Planch. ex Benth.
2D NMR
Cupanioidesosides
Lecaniodiscus cupanioides
Sapindaceae
Sesquiterpene glycosides
Journal
Carbohydrate research
ISSN: 1873-426X
Titre abrégé: Carbohydr Res
Pays: Netherlands
ID NLM: 0043535
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
02
06
2020
revised:
03
07
2020
accepted:
05
07
2020
pubmed:
7
8
2020
medline:
1
6
2021
entrez:
7
8
2020
Statut:
ppublish
Résumé
Chemical investigation of the methanol extract of the roots of Lecaniodiscus cupanioides led to the isolation and characterisation of three new sesquiterpene glycosides, named cupanioidesosides A (1), B (2) and C (3), together with one new triterpenoid saponin named lecanioside A (4), Their structures were established by extensive analysis of spectroscopic methods including 1D and 2D NMR techniques (COSY, NOESY, TOCSY, HSQC, and HMBC) and HRESIMS. The four new compounds were evaluated for their antiproliferative activity against the Caco-2 cell line (human epithelial cell line). None of the isolated compounds showed positive activity in our assay. Our findings represent a valuable contribution to the chemotaxonomy Lecaniodiscus genus of the subfamily of Sapindoideae of Sapindaceae family, known to be a rich source of farnesol glycosides.
Identifiants
pubmed: 32755723
pii: S0008-6215(20)30342-6
doi: 10.1016/j.carres.2020.108092
pii:
doi:
Substances chimiques
Glycosides
0
Plant Extracts
0
Triterpenes
0
Farnesol
4602-84-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
108092Informations de copyright
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