SARS-CoV-2-host dynamics: Increased risk of adverse outcomes of COVID-19 in obesity.
COVID-19
Obesity
SARS-CoV-2
Journal
Diabetes & metabolic syndrome
ISSN: 1878-0334
Titre abrégé: Diabetes Metab Syndr
Pays: Netherlands
ID NLM: 101462250
Informations de publication
Date de publication:
Historique:
received:
18
05
2020
revised:
15
07
2020
accepted:
16
07
2020
pubmed:
7
8
2020
medline:
26
9
2020
entrez:
7
8
2020
Statut:
ppublish
Résumé
The pandemic of COVID-19 has put forward the public health system across countries to prepare themselves for the unprecedented outbreak of the present time. Recognition of the associated risks of morbidity and mortality becomes not only imperative but also fundamental to determine the prevention strategies as well as targeting the high-risk populations for appropriate therapies. We reviewed, collated and analysed the online database i.e. Pubmed, Google scholar, Researchgate to highlight the demographic and mechanistic link between obesity and associated risks of severity in COVID-19. We observed a changing dynamic in the reporting from the time of initial pandemic in China to currently reported research. While, initially body mass index (BMI) did not find a mention in the data, it is now clearly emerging that obesity is one of the profound risk factors for complications of COVID-19. Our review will help clinicians and health policy makers in considering the importance of obesity in making the prevention and therapeutic strategies of COVID-19. An extra attention and precaution for patients with obesity in COVID-19 pandemic is recommended.
Sections du résumé
BACKGROUND AND AIM
OBJECTIVE
The pandemic of COVID-19 has put forward the public health system across countries to prepare themselves for the unprecedented outbreak of the present time. Recognition of the associated risks of morbidity and mortality becomes not only imperative but also fundamental to determine the prevention strategies as well as targeting the high-risk populations for appropriate therapies.
METHODS
METHODS
We reviewed, collated and analysed the online database i.e. Pubmed, Google scholar, Researchgate to highlight the demographic and mechanistic link between obesity and associated risks of severity in COVID-19.
RESULTS
RESULTS
We observed a changing dynamic in the reporting from the time of initial pandemic in China to currently reported research. While, initially body mass index (BMI) did not find a mention in the data, it is now clearly emerging that obesity is one of the profound risk factors for complications of COVID-19.
CONCLUSION
CONCLUSIONS
Our review will help clinicians and health policy makers in considering the importance of obesity in making the prevention and therapeutic strategies of COVID-19. An extra attention and precaution for patients with obesity in COVID-19 pandemic is recommended.
Identifiants
pubmed: 32755835
pii: S1871-4021(20)30278-2
doi: 10.1016/j.dsx.2020.07.030
pmc: PMC7372253
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1355-1360Informations de copyright
Copyright © 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest Rakhee Yadav: Conceptualization, Data curation, Formal analysis, Writing - original draft, review & editing, Design, Literature search, Data acquisition, Data analysis, Manuscript Preparation, Manuscript editing, Manuscript review, Guarantor, Sandeep Aggarwal: Conceptualization, Writing - review & editing, Concepts, Contribution to intellectual content, Literature search, Manuscript editing, Manuscript review, Archna Singh: Formal analysis, Writing - review & editing, Contribution to intellectual content, Data analysis, Manuscript editing, Manuscript review.
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