Women with Schizophrenia over the Life Span: Health Promotion, Treatment and Outcomes.


Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
03 08 2020
Historique:
received: 16 06 2020
revised: 22 07 2020
accepted: 30 07 2020
entrez: 7 8 2020
pubmed: 7 8 2020
medline: 18 11 2020
Statut: epublish

Résumé

Women with schizophrenia show sex-specific health needs that differ according to stage of life. The aim of this narrative review is to resolve important questions concerning the treatment of women with schizophrenia at different periods of their life-paying special attention to reproductive and post-reproductive stages. Review results suggest that menstrual cycle-dependent treatments may be a useful option for many women and that recommendations re contraceptive options need always to be part of care provision. The pregnancy and the postpartum periods-while constituting vulnerable time periods for the mother-require special attention to antipsychotic effects on the fetus and neonate. Menopause and aging are further vulnerable times, with extra challenges posed by associated health risks. Pregnancy complications, neurodevelopmental difficulties of offspring, cancer risk and cognitive defects are indirect results of the interplay of hormones and antipsychotic treatment of women over the course of the lifespan. The literature recommends that health promotion strategies need to be directed at lifestyle modifications, prevention of medical comorbidities and increased psychosocial support. Careful monitoring of pharmacological treatment has been shown to be critical during periods of hormonal transition. Not only does treatment of women with schizophrenia often need to be different than that of their male peers, but it also needs to vary over the course of life.

Identifiants

pubmed: 32756418
pii: ijerph17155594
doi: 10.3390/ijerph17155594
pmc: PMC7432627
pii:
doi:

Substances chimiques

Antipsychotic Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

JL has received honoraria for lectures or advisory board membership from Janssen, Otsuka, Lundbeck and Angelini. AGR, AGD, AA and MB have received honoraria or travel funds for congresses from Janssen, Otsuka, Lundbeck and Angelini.

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Auteurs

Alexandre González-Rodríguez (A)

Department of Mental Health, Parc Taulí University Hospital, Institut d'Investigació i Innovació Parc Taulí (I3PT), Autonomous University of Barcelona (UAB), 08280 Sabadell, Barcelona, Spain.

Armand Guàrdia (A)

Department of Mental Health, Parc Taulí University Hospital, 08280 Sabadell, Barcelona, Spain.

Aida Álvarez Pedrero (A)

Department of Mental Health, Parc Taulí University Hospital, Institut d'Investigació i Innovació Parc Taulí (I3PT), Autonomous University of Barcelona (UAB), 08280 Sabadell, Barcelona, Spain.

Maria Betriu (M)

Department of Mental Health, Parc Taulí University Hospital, 08280 Sabadell, Barcelona, Spain.

Jesús Cobo (J)

Department of Mental Health, Parc Taulí University Hospital, Institut d'Investigació i Innovació Parc Taulí (I3PT), Autonomous University of Barcelona (UAB), 08280 Sabadell, Barcelona, Spain.

Sidharta Acebillo (S)

Department of Mental Health, Parc Taulí University Hospital, Institut d'Investigació i Innovació Parc Taulí (I3PT), Autonomous University of Barcelona (UAB), 08280 Sabadell, Barcelona, Spain.

José Antonio Monreal (JA)

Department of Mental Health, Parc Taulí University Hospital, Institut d'Investigació i Innovació Parc Taulí (I3PT), Autonomous University of Barcelona (UAB), 08280 Sabadell, Barcelona, Spain.

Mary V Seeman (MV)

Department of Psychiatry, University of Toronto, Toronto, ON M5P 3L6, Canada.

Diego Palao (D)

Department of Mental Health, Parc Taulí University Hospital, Institut d'Investigació i Innovació Parc Taulí (I3PT), Autonomous University of Barcelona (UAB), 08280 Sabadell, Barcelona, Spain.

Javier Labad (J)

Department of Mental Health, Parc Taulí University Hospital, Institut d'Investigació i Innovació Parc Taulí (I3PT), Autonomous University of Barcelona (UAB), 08280 Sabadell, Barcelona, Spain.

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