The association of hyperglycaemia and insulin resistance with incident depressive symptoms over 4 years of follow-up: The Maastricht Study.
Depression
Depressive symptoms
Epidemiology
Hyperglycaemia
Insulin resistance
Population-based cohort study
Type 2 diabetes mellitus
Journal
Diabetologia
ISSN: 1432-0428
Titre abrégé: Diabetologia
Pays: Germany
ID NLM: 0006777
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
03
03
2020
accepted:
22
06
2020
pubmed:
7
8
2020
medline:
3
11
2021
entrez:
7
8
2020
Statut:
ppublish
Résumé
Depression is twice as common in individuals with type 2 diabetes as in the general population. However, it remains unclear whether hyperglycaemia and insulin resistance are directly involved in the aetiology of depression. Therefore, we investigated the association of markers of hyperglycaemia and insulin resistance, measured as continuous variables, with incident depressive symptoms over 4 years of follow-up. We used data from the longitudinal population-based Maastricht Study (n = 2848; mean age 59.9 ± 8.1 years, 48.8% women, 265 incident depression cases, 10,932 person-years of follow-up). We assessed hyperglycaemia by fasting and 2 h post-load OGTT glucose levels, HbA Fasting plasma glucose, 2 h post-load glucose and HbA The observed temporal association between hyperglycaemia and incident depressive symptoms in this study supports the presence of a mechanistic link between hyperglycaemia and the development of depressive symptoms. Graphical abstract.
Identifiants
pubmed: 32757152
doi: 10.1007/s00125-020-05247-9
pii: 10.1007/s00125-020-05247-9
pmc: PMC7527373
doi:
Substances chimiques
Biomarkers
0
Blood Glucose
0
Glycated Hemoglobin A
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2315-2328Références
Lancet Neurol. 2013 Aug;12(8):822-38
pubmed: 23867200
Psychosom Med. 2014 Sep;76(7):555-61
pubmed: 25077428
JAMA Psychiatry. 2017 Jul 1;74(7):729-739
pubmed: 28564681
Br J Psychiatry. 2010 Nov;197(5):372-7
pubmed: 21037214
Diabetologia. 2004 Jul;47(7):1324-1330
pubmed: 15243705
Diabetes Care. 2010 Jul;33(7):e93
pubmed: 20587713
Nord J Psychiatry. 2015;69(7):497-508
pubmed: 25736983
PLoS One. 2013;8(2):e56300
pubmed: 23441174
Diabetes Care. 2016 Dec;39(12):2126-2140
pubmed: 27879358
Eur Neuropsychopharmacol. 2015 Oct;25(10):1532-43
pubmed: 26169573
Psychosom Med. 2014 Jun;76(5):363-9
pubmed: 24846000
J Am Geriatr Soc. 2015 Feb;63(2):393-5
pubmed: 25688617
Curr Diabetes Rev. 2009 May;5(2):112-9
pubmed: 19442096
Am J Geriatr Psychiatry. 2015 Aug;23(8):872-80
pubmed: 25532417
J Affect Disord. 2012 Oct;142 Suppl:S8-21
pubmed: 23062861
J Clin Psychiatry. 1998;59 Suppl 20:22-33;quiz 34-57
pubmed: 9881538
J Affect Disord. 2012 Oct;142 Suppl:S42-55
pubmed: 23062857
F1000Res. 2018 Aug 14;7:
pubmed: 30135724
World J Diabetes. 2010 May 15;1(2):36-47
pubmed: 21537426
Arch Gen Psychiatry. 2012 Apr;69(4):410-7
pubmed: 22147809
Diabetologia. 2012 Mar;55(3):608-16
pubmed: 22198261
Diabetes Care. 2018 Mar;41(3):e31-e32
pubmed: 29463671
Diabetes Metab Syndr Obes. 2014 Dec 04;7:587-91
pubmed: 25506234
Diabetes Care. 2013 Apr;36(4):928-34
pubmed: 23230097
Psychol Med. 2014 May;44(7):1403-16
pubmed: 23942242
Pharmacol Ther. 2012 Oct;136(1):82-93
pubmed: 22820012
BMJ. 2005 Mar 26;330(7493):705-6
pubmed: 15684022
Eur J Epidemiol. 2014 Jun;29(6):439-51
pubmed: 24756374
Diabetes Care. 1999 Sep;22(9):1462-70
pubmed: 10480510
Psychosom Med. 2016 Feb-Mar;78(2):233-41
pubmed: 26452174
Diabetes. 2018 Sep;67(9):1729-1741
pubmed: 30135134
Depress Anxiety. 2017 Jan;34(1):59-67
pubmed: 27271340
Eur J Pharmacol. 2004 Apr 19;490(1-3):187-97
pubmed: 15094085
Acta Diabetol. 2016 Aug;53(4):589-98
pubmed: 26923701
Endocrinol Metab Clin North Am. 2013 Sep;42(3):529-44
pubmed: 24011885
Diabetes Care. 2004 Jun;27(6):1487-95
pubmed: 15161807
Diabetes Care. 2013 Jan;36(1):166-75
pubmed: 23264288
JAMA. 2008 Jun 18;299(23):2751-9
pubmed: 18560002
Prog Neurobiol. 2009 Aug;88(4):246-63
pubmed: 19427352
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 Jan;54(1):98-107
pubmed: 21246335
Mol Psychiatry. 2018 Feb;23(2):335-343
pubmed: 27752078
J Gen Intern Med. 2001 Sep;16(9):606-13
pubmed: 11556941
Neurochem Res. 2007 Oct;32(10):1749-56
pubmed: 17705097
J Diabetes Complications. 2017 Nov;31(11):1608-1613
pubmed: 28865713
J Am Geriatr Soc. 2016 Nov;64(11):e201-e206
pubmed: 27783384
Diabetes Res Clin Pract. 2013 Feb;99(2):98-104
pubmed: 23265924