Surface-modified mesoporous nanofibers for microfluidic immunosensor with an ultra-sensitivity and high signal-to-noise ratio.

Biosensing Techniques Immunoassay Microfluidics Nanofibers Signal-To-Noise Ratio
Mesoporous nanofibers Microfluidic immunosensor Sensitivity Signal-to-noise ratio Surface modification

Journal

Biosensors & bioelectronics
ISSN: 1873-4235
Titre abrégé: Biosens Bioelectron
Pays: England
ID NLM: 9001289

Informations de publication

Date de publication:
15 Oct 2020
Historique:
received: 20 04 2020
revised: 17 06 2020
accepted: 09 07 2020
pubmed: 8 8 2020
medline: 15 5 2021
entrez: 8 8 2020
Statut: ppublish

Résumé

How to balance the sensitivity and signal-to-noise ratio of immunosensor remains many challenges during various diseases diagnosis. Here we develop a new microfluidic immunosensor based on surface-modified mesoporous nanofibers, and simultaneously realize an ultra-sensitivity and high signal-to-noise ratio for the detection of multiple biomarkers. In the current study, we fabricated titanium dioxide (TiO

Identifiants

DOI: 10.1016/j.bios.2020.112444 PMID: 32758910
pubmed: 32758910
pii: S0956-5663(20)30438-3
doi: 10.1016/j.bios.2020.112444
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112444

Informations de copyright

Copyright © 2020. Published by Elsevier B.V.

Auteurs

Zulan Li (Z)

PLA Medical College and Clinical Laboratory of Second Medical Center of PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, China.

Ye Liu (Y)

Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, 650000, China. Electronic address: liuye@imbcams.com.cn.

Xingming Chen (X)

Laboratory Department of PLA Strategic Support Force Characteristic Medical Center, Beijing, 100101, China.

Hongyan Cao (H)

PLA Medical College and Clinical Laboratory of Second Medical Center of PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, China.

Haiying Shen (H)

Department of Biomedical Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Rd, Nanshan District, Shenzhen, Guangdong, 518055, China.

Lei Mou (L)

Department of Biomedical Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Rd, Nanshan District, Shenzhen, Guangdong, 518055, China.

Xinli Deng (X)

PLA Medical College and Clinical Laboratory of Second Medical Center of PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, China.

Xingyu Jiang (X)

Department of Biomedical Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Rd, Nanshan District, Shenzhen, Guangdong, 518055, China.

Yulong Cong (Y)

PLA Medical College and Clinical Laboratory of Second Medical Center of PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, China.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Techniques de biocapteur › Surface-modified mesoporous nanofibers for...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Dosage immunologique › Surface-modified mesoporous nanofibers for...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Miniaturisation › Microtechnologie › Microfluidique › Surface-modified mesoporous nanofibers for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanofibres › Surface-modified mesoporous nanofibers for...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Sensibilité et spécificité › Rapport signal-bruit › Surface-modified mesoporous nanofibers for...