Review of 177Lu-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer.

prostate cancer prostate specific membrane antigen radio-ligand therapy

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
30 Jun 2020
Historique:
entrez: 8 8 2020
pubmed: 8 8 2020
medline: 8 8 2020
Statut: epublish

Résumé

Prostate-specific membrane antigen (PSMA) is a cell membrane glycoprotein that is selectively expressed in prostate cells, with expression levels increasing dramatically in prostatic adenocarcinoma. PSMA-based radioligand therapy (RLT) has emerged as a viable therapeutic modality for the treatment of progressive metastatic prostate cancer. One commonly employed combination involves lutetium-177 conjugated to the ligand PSMA-617 (

Identifiants

pubmed: 32760622
doi: 10.7759/cureus.8921
pmc: PMC7392183
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e8921

Informations de copyright

Copyright © 2020, Sun et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Michael Sun (M)

Internal Medicine, Weill Cornell Medicine, New York, USA.

Muhammad O Niaz (MO)

Internal Medicine, Sharif Medical City Hospital, Lahore, PAK.

Adlai Nelson (A)

Urology, Weill Cornell Medicine, New York, USA.

Myrto Skafida (M)

Radiology, Weill Cornell Medicine, New York, USA.

Muhammad J Niaz (MJ)

Urology, Weill Cornell Medicine, New York, USA.

Classifications MeSH