Aneurysmal bone cyst inadvertently treated with chemotherapy-A series of three cases.


Journal

Pediatric blood & cancer
ISSN: 1545-5017
Titre abrégé: Pediatr Blood Cancer
Pays: United States
ID NLM: 101186624

Informations de publication

Date de publication:
10 2020
Historique:
received: 12 05 2020
revised: 29 06 2020
accepted: 17 07 2020
pubmed: 8 8 2020
medline: 5 1 2021
entrez: 8 8 2020
Statut: ppublish

Résumé

Aneurysmal bone cyst (ABC) is a benign locally aggressive tumor that occurs in childhood and early adulthood. Most relevant differential diagnoses are the telangiectatic osteosarcoma and the giant cell tumor. In the present case series chemotherapy following the EURAMOS or the Euro-Ewing 99 protocol was externally applied in three patients with the misdiagnosis of ABC as malignant bone tumor. In all three cases, a significant reduction of the volume of the ABC was achieved. This is the first report about the use of neoadjuvant chemotherapy in ABC. Chemotherapy reduces the size of an ABC and leads to progressive sclerosis.

Identifiants

pubmed: 32761959
doi: 10.1002/pbc.28638
doi:

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e28638

Informations de copyright

© 2020 The Authors. Pediatric Blood & Cancer published by Wiley Periodicals LLC.

Références

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Auteurs

Niklas Deventer (N)

Department of Orthopedics and Tumororthopedics, University Hospital Munster, Muenster, Germany.

Nils Deventer (N)

Department of Orthopedics and Tumororthopedics, University Hospital Munster, Muenster, Germany.

Georg Gosheger (G)

Department of Orthopedics and Tumororthopedics, University Hospital Munster, Muenster, Germany.

Tymoteusz Budny (T)

Department of Orthopedics and Tumororthopedics, University Hospital Munster, Muenster, Germany.

Marieke de Vaal (M)

Department of Orthopedics and Tumororthopedics, University Hospital Munster, Muenster, Germany.

Arne Riegel (A)

Department of Clinical Radiology, University Hospital Munster, Muenster, Germany.

Birthe Heitkoetter (B)

Gerhard-Domagk-Institute of Pathology, University Hospital Munster, Muenster, Germany.

Torsten Kessler (T)

Department of Medicine A, University Hospital Munster, Muenster, Germany.

Monika Poeppelmann (M)

Gerhard-Domagk-Institute of Pathology, University Hospital Munster, Muenster, Germany.

Claudia Rossig (C)

Department of Pediatric Hematology and Oncology, University Hospital Munster, Muenster, Germany.

Heribert Juergens (H)

Department of Pediatric Hematology and Oncology, University Hospital Munster, Muenster, Germany.

Timo Luebben (T)

Department of Orthopedics and Tumororthopedics, University Hospital Munster, Muenster, Germany.

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