Defining gaps in pre-exposure prophylaxis delivery for pregnant and post-partum women in high-burden settings using an implementation science framework.

Anti-HIV Agents / administration & dosage Female HIV Infections / prevention & control Health Plan Implementation Humans Infectious Disease Transmission, Vertical / prevention & control Male Postnatal Care Pre-Exposure Prophylaxis Pregnancy

Journal

The lancet. HIV
ISSN: 2352-3018
Titre abrégé: Lancet HIV
Pays: Netherlands
ID NLM: 101645355

Informations de publication

Date de publication:
08 2020
Historique:
received: 16 01 2020
revised: 20 03 2020
accepted: 24 03 2020
entrez: 9 8 2020
pubmed: 9 8 2020
medline: 1 9 2020
Statut: ppublish

Résumé

Pregnancy is a high-risk period for HIV acquisition in African women, and pregnant women who become acutely infected with HIV account for up to a third of vertical HIV transmission cases in African settings. To protect women and eliminate vertical transmission, WHO recommends offering oral pre-exposure prophylaxis (PrEP) based on tenofovir to HIV-negative pregnant and post-partum women with a substantial risk of HIV acquisition. PrEP implementation for pregnant and post-partum women lags behind implementation for other high-risk populations. Unique considerations for PrEP implementation arise during pregnancy and post partum, including the integration of provider training with clinical delivery and monitoring of PrEP exposure and outcomes within existing maternal health systems, yet scarce implementation data are available to generate evidence in this context.

Identifiants

DOI: 10.1016/S2352-3018(20)30102-8 PMID: 32763221 PMC: PMC7587402
pubmed: 32763221
pii: S2352-3018(20)30102-8
doi: 10.1016/S2352-3018(20)30102-8
pmc: PMC7587402
mid: NIHMS1607983
pii:
doi:

Substances chimiques

Anti-HIV Agents 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

e582-e592

Subventions

Organisme : NIAID NIH HHS
ID : K24 AI120796
Pays : United States
Organisme : NIAID NIH HHS
ID : L30 AI140785
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD094630
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI131060
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI027757
Pays : United States
Organisme : World Health Organization
ID : 001
Pays : International
Organisme : FIC NIH HHS
ID : K01 TW011187
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI125498
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH116771
Pays : United States
Organisme : NIMH NIH HHS
ID : K01 MH121124
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD100201
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH095507
Pays : United States

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

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Auteurs

Jillian Pintye (J)

Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA; Department of Global Health, University of Washington, Seattle, WA, USA. Electronic address: jpintye@uw.edu.

Dvora L Joseph Davey (DLJ)

Department of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA; Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

Anjuli D Wagner (AD)

Department of Global Health, University of Washington, Seattle, WA, USA.

Grace John-Stewart (G)

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA.

Rachel Baggaley (R)

World Health Organization, Geneva, Switzerland.

Linda-Gail Bekker (LG)

Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa.

Connie Celum (C)

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA.

Benjamin H Chi (BH)

Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA.

Thomas J Coates (TJ)

Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Allison K Groves (AK)

Department of Community Health and Prevention, Drexel University, Philadelphia, PA, USA.

Jessica E Haberer (JE)

Center for Global Health, Massachusetts General Hospital, Boston, MA, USA.

Renee Heffron (R)

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA.

John Kinuthia (J)

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Research and Programs, Kenyatta National Hospital, Nairobi, Kenya.

Lynn T Matthews (LT)

Department of Medicine, University of Alabama, Birmingham, AL, USA.

James A McIntyre (JA)

Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa; Anova Health Institute, Johannesburg, South Africa.

Dhayendre Moodley (D)

CAPRISA, University of KwaZulu Natal, Durban, South Africa.

Lynne M Mofenson (LM)

Elizabeth Glaser Pediatric AIDS Foundation, Washington, DC, USA.

Nelly Mugo (N)

Department of Global Health, University of Washington, Seattle, WA, USA; Kenya Medical Research Institute (KEMRI), Center for Clinical Research, Nairobi, Kenya.

Andrew Mujugira (A)

Department of Global Health, University of Washington, Seattle, WA, USA; Infectious Diseases Institute, Makerere University, Kampala, Uganda.

Landon Myer (L)

Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

Steven Shoptaw (S)

Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Lynda Stranix-Chibanda (L)

College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.

Jared M Baeten (JM)

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Antirétroviraux › Agents antiVIH › Defining gaps in pre-exposure prophylaxis...
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Defining gaps in pre-exposure prophylaxis...
questionsmedicales.fr › Organisations et économie des soins de santé › Mise en oeuvre des programmes de santé › Defining gaps in pre-exposure prophylaxis...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Defining gaps in pre-exposure prophylaxis...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Transmission de maladie infectieuse › Transmission verticale de maladie infectieuse › Defining gaps in pre-exposure prophylaxis...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Soins aux patients › Soins périnatals › Prise en charge postnatale › Defining gaps in pre-exposure prophylaxis...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Prophylaxie pré-exposition › Defining gaps in pre-exposure prophylaxis...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Defining gaps in pre-exposure prophylaxis...