Coronavirus diseases 2019: Current biological situation and potential therapeutic perspective.

Animals COVID-19 Coronavirus Infections / diagnosis Disease Susceptibility Genomics Humans Pandemics Pneumonia, Viral / diagnosis
COVID-19 Coronavirus Mortality Pathogenicity SARS-CoV-2 Treatment

Journal

European journal of pharmacology
ISSN: 1879-0712
Titre abrégé: Eur J Pharmacol
Pays: Netherlands
ID NLM: 1254354

Informations de publication

Date de publication:
05 Nov 2020
Historique:
received: 26 05 2020
revised: 19 07 2020
accepted: 29 07 2020
pubmed: 9 8 2020
medline: 27 10 2020
entrez: 9 8 2020
Statut: ppublish

Résumé

Coronavirus Disease 2019 (COVID-19) caused by a Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) was first reported in Wuhan, China at the end of December 2019. SARS-CoV-2 is a highly pathogenic zoonotic virus and closely related to the Severe Acute Respiratory Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The COVID-19 was declared as a global pandemic due to its high infectiousness, and worldwide morbidities and mortalities. The Chinese scientists at the start of the outbreak reported genome sequences, which made the characterization of glycoproteins and other structural proteins possible. Moreover, researchers across the world have widely focused on understanding basic biology, developing vaccines, and therapeutic drugs against the COVID-19. However, until now, no promising treatment options, as well as vaccines, are available. In this review, we have described SARS-CoV-2's genome, transmission, and pathogenicity. We also discussed novel potential therapeutic agents that can help to treat the COVID-19 patients.

Identifiants

DOI: 10.1016/j.ejphar.2020.173447 PMID: 32763302 PMC: PMC7403098
pubmed: 32763302
pii: S0014-2999(20)30539-2
doi: 10.1016/j.ejphar.2020.173447
pmc: PMC7403098
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

173447

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

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Auteurs

Suliman Khan (S)

Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.

Huseyin Tombuloglu (H)

Department of Genetics, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P. O. Box 1982, Dammam, 31441, Saudi Arabia.

Sameh E Hassanein (SE)

Bioinformatics Dept., Agricultural Genetic Engineering Research Institute (AGERI), Bioinformatics and Functional Genomics Dept., College of Biotechnology, Misr University for Science and Technology, P. O. Box 77, Giza, Egypt.

Suriya Rehman (S)

Department of Epidemic Diseases Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, 31441, Dammam, Saudi Arabia.

Ayhan Bozkurt (A)

Department of Physics, Institute for Medical Research and Consultations, Imam Abdulrahman Bin Faisal University, P. O. Box: 1982, 31441, Dammam, Saudi Arabia.

Emre Cevik (E)

Department of Genetics, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P. O. Box 1982, Dammam, 31441, Saudi Arabia.

Shaimaa Abdel-Ghany (S)

Department of Environmental Biotechnology, College of Biotechnology, Misr University for Science and Technology, P. O. Box 77, Giza, Egypt.

Ghulam Nabi (G)

Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei Province, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, PR China.

Ashaq Ali (A)

Wuhan Institute of Virology, Chinese Academy of Sciences Xiao Hong Shan No.44, Wuhan, PR China; University of Chinese Academy of Sciences, Beijing, 100049, China.

Hussein Sabit (H)

Department of Genetics, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P. O. Box 1982, Dammam, 31441, Saudi Arabia. Electronic address: hhsabit@iau.edu.sa.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Coronavirus diseases 2019: Current biological...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Coronavirus diseases 2019: Current biological...
questionsmedicales.fr › Infection › Maladies virales › Infections à virus à ARN › Infections à Nidovirales › Infections à Coronaviridae › Infections à coronavirus › Coronavirus diseases 2019: Current biological...
questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Prédisposition aux maladies › Coronavirus diseases 2019: Current biological...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › Coronavirus diseases 2019: Current biological...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Coronavirus diseases 2019: Current biological...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Épidémies de maladies › Épidémies › Pandémies › Coronavirus diseases 2019: Current biological...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › Coronavirus diseases 2019: Current biological...