Elevated Levels of Galectin-9 but Not Osteopontin in HIV and Tuberculosis Infections Indicate Their Roles in Detecting MTB Infection in HIV Infected Individuals.

HIV HIV/tuberculosis co-infection extrapulmonary tuberculosis galectin-9 latent tuberculosis osteopontin pulmonary tuberculosis

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2020
Historique:
received: 09 03 2020
accepted: 29 06 2020
entrez: 9 8 2020
pubmed: 9 8 2020
medline: 9 8 2020
Statut: epublish

Résumé

Galectin-9 (Gal-9) and osteopontin (OPN) play immunomodulatory roles in tuberculosis and HIV infections. Evaluation of their levels as well as their interplay with different pro-inflammatory cytokines is critical to understand their role in immunopathogenesis of HIV/tuberculosis co-infection considering the complexity of the disease. Plasma levels of these proteins were measured by ELISAs in HIV-negative individuals with pulmonary (

Identifiants

pubmed: 32765475
doi: 10.3389/fmicb.2020.01685
pmc: PMC7380070
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1685

Informations de copyright

Copyright © 2020 Shete, Bichare, Pujari, Virkar, Thakar, Ghate, Patil, Vyakarnam, Gangakhedkar, Bai, Niki and Hattori.

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Auteurs

Ashwini Shete (A)

ICMR-National AIDS Research Institute, Pune, India.

Shubhangi Bichare (S)

ICMR-National AIDS Research Institute, Pune, India.

Vishwanath Pujari (V)

B. J. Medical College and Sassoon General Hospital, Pune, India.

Rashmi Virkar (R)

Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth Deemed University, Pune, India.

Madhuri Thakar (M)

ICMR-National AIDS Research Institute, Pune, India.

Manisha Ghate (M)

ICMR-National AIDS Research Institute, Pune, India.

Sandip Patil (S)

ICMR-National AIDS Research Institute, Pune, India.

Annapurna Vyakarnam (A)

Indian Institute of Science (IISc), Bengaluru, India.

Raman Gangakhedkar (R)

Indian Council of Medical Research, New Delhi, India.

Gaowa Bai (G)

Department of Health Science and Social Welfare, Kibi International University, Takahashi, Japan.

Toshiro Niki (T)

Department of Immunology, Faculty of Medicine, Kagawa University, Kita-gun, Japan.

Toshio Hattori (T)

Department of Health Science and Social Welfare, Kibi International University, Takahashi, Japan.

Classifications MeSH