Effects of IL-34 on Macrophage Immunological Profile in Response to Alzheimer's-Related Aβ

Alzheimer Disease / immunology Amyloid beta-Peptides / metabolism Animals CD36 Antigens / metabolism Cells, Cultured Humans Interleukins / immunology Macrophage Colony-Stimulating Factor / metabolism Macrophages / physiology Matrix Metalloproteinase 9 / metabolism Mice Mice, Inbred C57BL Peptide Fragments / metabolism Phagocytosis Protein Multimerization
Alzheimer's disease IL34 MCSF amyloid-beta macrophage myeloid cells phagocytosis scavenger receptors

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2020
Historique:
received: 04 03 2020
accepted: 04 06 2020
entrez: 9 8 2020
pubmed: 9 8 2020
medline: 20 4 2021
Statut: epublish

Résumé

Interleukin-34 (IL-34) is a recently discovered cytokine that acts as a second ligand of the colony stimulating factor 1 receptor (CSF1R) in addition to macrophage colony-stimulating factor (M-CSF). Similar to M-CSF, IL-34 also stimulates bone marrow (BM)-derived monocyte survival and differentiation into macrophages. Growing evidence suggests that peripheral BM-derived monocyte/macrophages (BMMO) play a key role in the physiological clearance of cerebral amyloid β-protein (Aβ). Aβ

Identifiants

DOI: 10.3389/fimmu.2020.01449 PMID: 32765504 PMC: PMC7378440
pubmed: 32765504
doi: 10.3389/fimmu.2020.01449
pmc: PMC7378440
doi:

Substances chimiques

Amyloid beta-Peptides 0
CD36 Antigens 0
IL34 protein, human 0
Interleukins 0
Peptide Fragments 0
amyloid beta-protein (1-42) 0
Macrophage Colony-Stimulating Factor 81627-83-0
Matrix Metalloproteinase 9 EC 3.4.24.35

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1449

Subventions

Organisme : NIA NIH HHS
ID : R01 AG055865
Pays : United States

Informations de copyright

Copyright © 2020 Zuroff, Torbati, Hart, Fuchs, Sheyn, Rentsendorj, Koronyo, Hayden, Teplow, Black and Koronyo-Hamaoui.

Références

EMBO Mol Med. 2016 Jun 01;8(6):595-608
pubmed: 27025652
Nat Rev Mol Cell Biol. 2007 Feb;8(2):101-12
pubmed: 17245412
Biol Chem. 2014 Oct;395(10):1173-8
pubmed: 24633750
J Cell Physiol. 2018 Sep;233(9):6425-6440
pubmed: 29319160
Brain. 2019 Jan 1;143(1):336-358
pubmed: 31794021
Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):330-5
pubmed: 12506200
Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12849-54
pubmed: 17652175
Acc Chem Res. 2004 Jun;37(6):357-64
pubmed: 15196045
Biochim Biophys Acta. 2015 May;1853(5):1010-21
pubmed: 25662098
J Bone Miner Metab. 2013 Sep;31(5):486-95
pubmed: 23740288
J Exp Med. 1991 Oct 1;174(4):827-36
pubmed: 1919437
J Biol Chem. 1999 Nov 5;274(45):32301-8
pubmed: 10542270
Methods Mol Biol. 2018;1784:29-33
pubmed: 29761385
Nat Rev Neurol. 2018 Nov;14(11):667-675
pubmed: 30266932
J Neurochem. 2009 Dec;111(6):1409-24
pubmed: 19780903
J Neurosci. 2004 Nov 3;24(44):9838-46
pubmed: 15525768
PLoS One. 2013;8(4):e60921
pubmed: 23577177
Am J Pathol. 2011 Oct;179(4):2016-27
pubmed: 21872563
Cytokine. 2017 Nov;99:139-147
pubmed: 28886491
Cell Death Differ. 2010 Dec;17(12):1917-27
pubmed: 20489731
Brain Behav Immun. 2018 Jan;67:163-180
pubmed: 28860067
Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17253-8
pubmed: 24101477
Brain. 2016 Mar;139(Pt 3):891-907
pubmed: 26747862
Methods Enzymol. 2006;413:217-36
pubmed: 17046399
Front Immunol. 2020 Jan 31;11:49
pubmed: 32082319
Science. 2002 Jul 19;297(5580):353-6
pubmed: 12130773
Ann Neurol. 2016 Jan;79(1):90-109
pubmed: 26505992
Immunity. 2012 Dec 14;37(6):1050-1060
pubmed: 23177320
Eur J Immunol. 2014 Jun;44(6):1575-81
pubmed: 24737461
Cold Spring Harb Perspect Biol. 2014 Jun 02;6(6):
pubmed: 24890514
Nat Med. 2008 Aug;14(8):837-42
pubmed: 18568035
Eur J Neurosci. 2007 Jul;26(2):413-6
pubmed: 17623022
Brain. 2009 Apr;132(Pt 4):1078-92
pubmed: 19151372
Am J Pathol. 1992 Jun;140(6):1389-99
pubmed: 1376558
J Neurosci. 1996 Dec 15;16(24):7910-9
pubmed: 8987819
J Neurosci. 2009 Apr 1;29(13):4252-62
pubmed: 19339619
J Leukoc Biol. 2010 Sep;88(3):495-505
pubmed: 20504948
PLoS One. 2013;8(2):e56045
pubmed: 23409120
Nature. 2006 Mar 16;440(7082):352-7
pubmed: 16541076
PLoS Med. 2009 Jul;6(7):e1000113
pubmed: 19636355
J Biol Chem. 2001 Sep 14;276(37):35176-84
pubmed: 11441003
Eur J Immunol. 2016 Mar;46(3):552-9
pubmed: 26634935
Structure. 2012 Apr 4;20(4):676-87
pubmed: 22483114
JCI Insight. 2017 Aug 17;2(16):
pubmed: 28814675
Front Aging Neurosci. 2017 Aug 09;9:244
pubmed: 28848420
J Alzheimers Dis. 2001 Feb;3(1):75-80
pubmed: 12214075
Neuron. 1996 Sep;17(3):553-65
pubmed: 8816718
Immunity. 2014 Jul 17;41(1):14-20
pubmed: 25035950
Neuron. 2006 Feb 16;49(4):489-502
pubmed: 16476660
J Leukoc Biol. 2018 Nov;104(5):931-951
pubmed: 30066957
Science. 2003 Apr 18;300(5618):486-9
pubmed: 12702875
Brain. 2015 Aug;138(Pt 8):2399-422
pubmed: 26049087
Neuron. 2017 Apr 19;94(2):237-248
pubmed: 28426958
Lab Invest. 2017 Jan;97(1):4-13
pubmed: 27869795
Nature. 2018 Aug;560(7717):185-191
pubmed: 30046111
Nat Immunol. 2012 Jun 24;13(8):753-60
pubmed: 22729249
CSH Protoc. 2008 Dec 01;2008:pdb.prot5080
pubmed: 21356739
Expert Rev Mol Diagn. 2020 Apr;20(4):421-441
pubmed: 32066283
J Vis Exp. 2010 Nov 16;(45):
pubmed: 21113117
Curr Opin Neurol. 2020 Feb;33(1):87-92
pubmed: 31789703
Am J Pathol. 2010 Jul;177(1):346-54
pubmed: 20522650
Sci Rep. 2015 Sep 29;5:14624
pubmed: 26416689
Biochim Biophys Acta. 2012 Jul;1824(7):938-45
pubmed: 22579672
Cytokine. 2013 Jul;63(1):10-17
pubmed: 23684409
Science. 2010 Dec 24;330(6012):1774
pubmed: 21148344
Acta Neuropathol. 2020 May;139(5):813-836
pubmed: 32043162
Sci Rep. 2018 Jan 10;8(1):256
pubmed: 29321503
J Neurochem. 2009 Oct;111(2):537-46
pubmed: 19686241
Acta Neuropathol. 1992;84(3):225-33
pubmed: 1414275
J Cell Biol. 1993 Jun;121(5):1011-20
pubmed: 8099075
Science. 2008 May 9;320(5877):807-11
pubmed: 18467591
Int J Alzheimers Dis. 2012;2012:489456
pubmed: 22666621
Neuron. 2002 Aug 1;35(3):419-32
pubmed: 12165466
J Biol Chem. 2006 Aug 25;281(34):24566-74
pubmed: 16787929
Neuroimage. 2011 Jan;54 Suppl 1:S204-17
pubmed: 20550967
J Neurosci. 2010 Jul 21;30(29):9651-8
pubmed: 20660248
J Alzheimers Dis. 2005 Jun;7(3):221-32; discussion 255-62
pubmed: 16006665
Neurosci Lett. 2012 Oct 31;529(1):86-91
pubmed: 22985514
Curr Hypertens Rep. 2020 Jan 8;22(1):4
pubmed: 31916032
Cell Mol Life Sci. 2017 Jun;74(12):2167-2201
pubmed: 28197669

Auteurs

Leah R Zuroff (LR)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Tania Torbati (T)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States.
Western University of Health Sciences College of Osteopathic Medicine of the Pacific, Pomona, CA, United States.

Nadav J Hart (NJ)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.

Dieu-Trang Fuchs (DT)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Julia Sheyn (J)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Altan Rentsendorj (A)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Yosef Koronyo (Y)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Eric Y Hayden (EY)

Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States.

David B Teplow (DB)

Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States.

Keith L Black (KL)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Maya Koronyo-Hamaoui (M)

Neurosurgery Department, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Department of Biomedical Sciences, Applied Cellular Biology and Physiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Peptides bêta-amyloïdes › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Eucaryotes › Animaux › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux lipoprotéines › Récepteurs aux lipoprotéines LDL › Récepteurs éboueurs › Récepteurs éboueurs de classe B › Antigènes CD36 › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Cellules › Cellules cultivées › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Facteurs de croissance hématopoïétique › Facteurs de stimulation des colonies › Facteur de stimulation des colonies de macrophages › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Secreted matrix metalloproteinases › Matrix metalloproteinase 9 › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Fragments peptidiques › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Phénomènes du système immunitaire › Phagocytose › Effects of IL-34 on Macrophage Immunological...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Multimérisation de protéines › Effects of IL-34 on Macrophage Immunological...