Posterior fossa assessment in the axial view of the head at 11-14 weeks of gestation in normal and aneuploid fetuses.

cisterna magna fetal posterior fossa first trimester anatomy first trimester screening fourth ventricle

Journal

Experimental and therapeutic medicine
ISSN: 1792-0981
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 10 04 2020
accepted: 11 05 2020
entrez: 9 8 2020
pubmed: 9 8 2020
medline: 9 8 2020
Statut: ppublish

Résumé

Posterior fossa ultrasound appearance may offer clues for brain anomalies as early as the first trimester. The purpose of the study was to find an easy, reproducible method to examine the posterior fossa. From January 2017 to March 2018, 132 consecutive pregnancies presenting for first-trimester screening, were selected at 11-14 weeks' gestation. An oblique axial view of the fetal head was routinely achieved with visualization of the posterior fossa, wherein the cisterna magna (CM) and the fourth ventricle (V4) anteroposterior diameter was measured. Moreover, 81 patients had a follow-up scan at 19-24 weeks, and the CM and transverse cerebellar diameter (TCD) were measured. Normal ranges were established at 11-14 weeks for CM and V4 according to crown-rump length (CRL). The 50th centile for CM ranges from 1.2 mm to 2.3 mm at a CRL between 45 and 85 mm. The V4 50th centile ranges from 1.8 to 2.4 mm. A positive correlation was found between the first-trimester and second-trimester CM diameter and between the first-trimester V4 and second-trimester TCD. There is an inverse correlation between the first-trimester CM and second-trimester TCD. The measurements of different components of the posterior fossa in the first trimester cannot predict the size of CM and TCD in the second trimester. The presence of the three hypoechoic structures (cerebral peduncles, V4, and CM) separated by two hyperechoic lines is easy to see and measure.

Identifiants

pubmed: 32765736
doi: 10.3892/etm.2020.8793
pii: ETM-0-0-8793
pmc: PMC7401706
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2470-2474

Informations de copyright

Copyright: © Zvanca et al.

Références

Fetal Diagn Ther. 2013;34(1):44-9
pubmed: 23615311
Fetal Diagn Ther. 2012;32(3):186-9
pubmed: 22846426
Ginekol Pol. 2018;89(4):205-10
pubmed: 29781076
Ultrasound Obstet Gynecol. 2009 Sep;34(3):249-52
pubmed: 19705402
Ultrasound Obstet Gynecol. 2010 Feb;35(2):133-8
pubmed: 20101633
Ultrasound Obstet Gynecol. 2008 Apr;31(4):388-96
pubmed: 18348183
Prenat Diagn. 2012 Sep;32(9):854-8
pubmed: 22692599
Ultrasound Obstet Gynecol. 2016 Jun;47(6):720-5
pubmed: 25914043
Prenat Diagn. 2011 Jan;31(1):103-6
pubmed: 21188735
Ultrasound Obstet Gynecol. 2011 Dec;38(6):722-6
pubmed: 21984530
Prenat Diagn. 2011 Dec;31(12):1189-92
pubmed: 22024986
Ultrasound Obstet Gynecol. 2011 Dec;38(6):620-4
pubmed: 21308843

Auteurs

Mona Elena Zvanca (ME)

Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, Elias University Hospital, 011461 Bucharest, Romania.

Alexandra Munteanu (A)

Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, Elias University Hospital, 011461 Bucharest, Romania.

Mihaela Bot (M)

Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, Elias University Hospital, 011461 Bucharest, Romania.

Aida Petca (A)

Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, Elias University Hospital, 011461 Bucharest, Romania.

Dragos Nemescu (D)

Department of Obstetrics and Gynecology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

Classifications MeSH