Preparedness and Reorganization of Care for Coronavirus Disease 2019 Patients in a Swiss ICU: Characteristics and Outcomes of 129 Patients.

acute respiratory distress syndrome coronavirus disease 2019 intensive care unit mortality severe acute respiratory syndrome coronavirus 2 surge capacity

Journal

Critical care explorations
ISSN: 2639-8028
Titre abrégé: Crit Care Explor
Pays: United States
ID NLM: 101746347

Informations de publication

Date de publication:
Aug 2020
Historique:
entrez: 9 8 2020
pubmed: 9 8 2020
medline: 9 8 2020
Statut: epublish

Résumé

In many countries, large numbers of critically ill patients with coronavirus disease 2019 are admitted to the ICUs within a short period of time, overwhelming usual care capacities. Preparedness and reorganization ahead of the wave to increase ICU surge capacity may be associated with favorable outcome. The purpose of this study was to report our experience in terms of ICU organization and anticipation, as well as reporting patient characteristics, treatment, and outcomes. A prospective observational study. The division of intensive care at the Geneva University Hospitals (Geneva, Switzerland). All consecutive adult patients with acute respiratory failure due to coronavirus disease 2019 admitted in the ICU between March 9, 2020, and May 19, 2020, were enrolled. Patients' demographic data, comorbidities, laboratory values, treatments, and clinical outcomes were collected. None. The ICU was reorganized into cells of six to eight patients under the care of three physicians and five nurses. Its capacity increased from 30 to 110 beds, fully equipped and staffed, transforming the surgical intermediate care unit, the postoperative care facility, and operating theaters into ICUs. Surge capacity has always exceeded the number of patients hospitalized. Among 129 critically ill patients with severe acute hypoxemic respiratory failure, 96% required invasive mechanical ventilation. A total of 105 patients (81%) were discharged alive and 24 died, corresponding to a mortality of 19%. Patients who died were significantly older, with higher severity scores at admission, had higher levels of d-dimers, plasma creatinine, high-sensitive troponin T, C-reactive protein, and procalcitonin, and required more frequent prone sessions. A rapid increase in ICU bed capacity, including adequate equipment and staffing, allowed for a large number of critically ill coronavirus disease 2019 patients to be taken care of within a short period of time. Anticipation and preparedness ahead of the wave may account for the low mortality observed in our center. These results highlight the importance of resources management strategy in the context of the ongoing coronavirus disease 2019 pandemic.

Identifiants

pubmed: 32766566
doi: 10.1097/CCE.0000000000000173
pmc: PMC7392615
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e0173

Informations de copyright

Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.

Déclaration de conflit d'intérêts

The authors have disclosed that they do not have any potential conflicts of interest.

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Auteurs

Steve Primmaz (S)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Christophe Le Terrier (C)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Noémie Suh (N)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

François Ventura (F)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Filippo Boroli (F)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Karim Bendjelid (K)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Sara Cereghetti (S)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Raphaël Giraud (R)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Claudia Heidegger (C)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Deborah Pugin (D)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Nils Siegenthaler (N)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Didier Tassaux (D)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Jean-Clément Cabrol (JC)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Nathan Dolet (N)

Department of Research, University Hospital of Caen, Caen, France.
Department of Pediatric Surgery, University Hospital of Caen, Caen, France.

Christoph Ellenberger (C)

Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Gleicy Keli Barcelos (G)

Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Marc-Joseph Licker (MJ)

Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Georges Savoldelli (G)

Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Eduardo Schiffer (E)

Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Angèle Gayet-Ageron (A)

Clinical Trial Unit, Division of Clinical Epidemiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Laurent Kaiser (L)

Division of Infectious Diseases, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Martin R Tramèr (MR)

Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Jérôme Pugin (J)

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Classifications MeSH