Risk Factors for Suicidal Ideation Following Mild Traumatic Brain Injury: A TRACK-TBI Study.
Journal
The Journal of head trauma rehabilitation
ISSN: 1550-509X
Titre abrégé: J Head Trauma Rehabil
Pays: United States
ID NLM: 8702552
Informations de publication
Date de publication:
Historique:
pubmed:
10
8
2020
medline:
16
10
2021
entrez:
10
8
2020
Statut:
ppublish
Résumé
To identify risk factors for suicidal ideation (SI) following mild traumatic brain injury (mTBI). Eleven US level 1 trauma centers. A total of 1158 emergency department patients with mTBI (Glasgow Coma Scale score = 13-15) enrolled in the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study. Prospective observational study; weights-adjusted multivariable logistic regression models (n's = 727-883) estimated associations of baseline factors and post-TBI symptoms with SI at 2 weeks and 3, 6, and 12 months postinjury. Patient Health Questionnaire, Rivermead Post-Concussion Symptoms Questionnaire. Preinjury psychiatric history predicted SI at all follow-ups (adjusted odds ratios [AORs] = 2.26-6.33, P values <.05) and history of prior TBI predicted SI at 2 weeks (AOR = 2.36, 95% confidence interval [CI] = 1.16-4.81, P = .018), 3 months (AOR = 2.62, 95% CI = 1.33-5.16, P = .005), and 6 months postinjury (AOR = 2.54, 95% CI = 1.19-5.42, P = .016). Adjusting for these baseline factors, post-TBI symptoms were strongly associated with SI at concurrent (AORs = 1.91-2.88 per standard deviation unit increase in Rivermead Post-Concussion Symptoms Questionnaire score; P values <.0005) and subsequent follow-up visits (AORs = 1.68-2.53; P values <.005). Most of the associations between post-TBI symptoms and SI were statistically explained by co-occurring depression. Screening for psychiatric and prior TBI history may help identify patients at risk for SI following mTBI. Awareness of the strong associations of post-TBI symptoms with SI may facilitate interventions to prevent suicide-related outcomes in patients with mTBI.
Identifiants
pubmed: 32769835
pii: 00001199-202101000-00011
doi: 10.1097/HTR.0000000000000602
pmc: PMC10134479
mid: NIHMS1735514
doi:
Banques de données
ClinicalTrials.gov
['NCT02119182']
Types de publication
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
E30-E39Subventions
Organisme : NICHD NIH HHS
ID : K23 HD087464
Pays : United States
Organisme : NINDS NIH HHS
ID : U01 NS086090
Pays : United States
Informations de copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The other authors declare no conflicts of interest.
Références
Centers for Disease Control and Prevention. TBI-related emergency department (ED) visits. https://www.cdc.gov/traumaticbraininjury/data/tbi-edhd.html . Updated March 29, 2019. Accessed August 28, 2019.
Centers for Disease Control and Prevention. Report to Congress on Traumatic Brain Injury in the United States: Epidemiology and Rehabilitation. Atlanta, GA: National Center for Injury Prevention and Control, Division of Unintentional Injury Prevention; 2015.
Ponsford J, Cameron P, Fitzgerald M, Grant M, Mikocka-Walus A. Long-term outcomes after uncomplicated mild traumatic brain injury: a comparison with trauma controls. J Neurotrauma. 2011;28(6):937–946.
McMahon P, Hricik A, Yue JK, et al. Symptomatology and functional outcome in mild traumatic brain injury: results from the prospective TRACK-TBI study. J Neurotrauma. 2014;31(1):26–33.
Nelson LD, Temkin NR, Dikmen S, et al. Recovery after mild traumatic brain injury in patients presenting to US level I trauma centers: a Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study. JAMA Neurol. 2019;76(9):1049–1059.
Fisher LB, Pedrelli P, Iverson GL, et al. Prevalence of suicidal behaviour following traumatic brain injury: longitudinal follow-up data from the NIDRR Traumatic Brain Injury Model Systems. Brain Inj. 2016;30(11):1311–1318.
Simpson G, Tate R. Suicidality in people surviving a traumatic brain injury: prevalence, risk factors and implications for clinical management. Brain Inj. 2007;21(13–14):1335–1351.
Simpson G, Tate R. Suicidality after traumatic brain injury: demographic, injury and clinical correlates. Psychol Med. 2002;32(4):687–697.
Ahmedani BK, Peterson EL, Hu Y, et al. Major physical health conditions and risk of suicide. Am J Prev Med. 2017;53(3):308–315.
Madsen T, Erlangsen A, Orlovska S, Mofaddy R, Nordentoft M, Benros ME. Association between traumatic brain injury and risk of suicide. JAMA. 2018;320(6):580–588.
Fazel S, Wolf A, Pillas D, Lichtenstein P, Langstrom N. Suicide, fatal injuries, and other causes of premature mortality in patients with traumatic brain injury: a 41-year Swedish population study. JAMA Psychiatry. 2014;71(3):326–333.
Phillips CJ, LeardMann CA, Vyas KJ, Crum-Cianflone NF, White MR. Risk factors associated with suicide completions among US enlisted marines. Am J Epidemiol. 2017;186(6):668–678.
Brenner LA, Ignacio RV, Blow FC. Suicide and traumatic brain injury among individuals seeking Veterans Health Administration services. J Head Trauma Rehabil. 2011;26(4):257–264.
Boggs JM, Beck A, Hubley S, et al. General medical, mental health, and demographic risk factors associated with suicide by firearm compared with other means. Psychiatr Serv. 2018;69(6):677–684.
Fralick M, Sy E, Hassan A, Burke MJ, Mostofsky E, Karsies T. Association of concussion with the risk of suicide: a systematic review and meta-analysis. JAMA Neurol. 2019;76(2):144–151.
Bryant RA, O'Donnell ML, Forbes D, McFarlane AC, Silove D, Creamer M. The course of suicide risk following traumatic injury. J Clin Psychiatry. 2016;77(5):648–653.
Wisco BE, Marx BP, Holowka DW, et al. Traumatic brain injury, PTSD, and current suicidal ideation among Iraq and Afghanistan U.S. veterans. J Trauma Stress. 2014;27(2):244–248.
Mackelprang JL, Bombardier CH, Fann JR, Temkin NR, Barber JK, Dikmen SS. Rates and predictors of suicidal ideation during the first year after traumatic brain injury. Am J Public Health. 2014;104(7):e100–e107.
Bethune A, da Costa L, van Niftrik CHB, Feinstein A. Suicidal ideation after mild traumatic brain injury: a consecutive Canadian sample. Arch Suicide Res. 2017;21(3):392–402.
Shura RD, Nazem S, Miskey HM, et al. Relationship between traumatic brain injury history and recent suicidal ideation in Iraq/Afghanistan-era veterans. Psychol Serv. 2019;16(2):312–320.
Lindquist LK, Love HC, Elbogen EB. Traumatic brain injury in Iraq and Afghanistan veterans: new results from a national random sample study. J Neuropsychiatry Clin Neurosci. 2017;29(3):254–259.
Bryan CJ, Clemans TA. Repetitive traumatic brain injury, psychological symptoms, and suicide risk in a clinical sample of deployed military personnel. JAMA Psychiatry. 2013;70(7):686–691.
Tsaousides T, Cantor JB, Gordon WA. Suicidal ideation following traumatic brain injury: prevalence rates and correlates in adults living in the community. J Head Trauma Rehabil. 2011;26(4):265–275.
Stein MB, Jain S, Giacino JT, et al. Risk of posttraumatic stress disorder and major depression in civilian patients after mild traumatic brain injury: a TRACK-TBI Study. JAMA Psychiatry. 2019;76(3):249–258.
Herrmann N, Rapoport MJ, Rajaram RD, et al. Factor analysis of the Rivermead Post-Concussion Symptoms Questionnaire in mild to moderate traumatic brain injury patients. J Neuropsychiatry Clin Neurosci. 2009;21(2):181–188.
Agtarap S, Campbell-Sills L, Thomas ML, Kessler RC, Ursano RJ, Stein MB. Postconcussive, posttraumatic stress and depressive symptoms in recently deployed U.S. Army soldiers with traumatic brain injury. Psychol Assess. 2019;31(11):1340–1356.
Campbell-Sills L, Stein MB, Liu H, et al. Associations of lifetime traumatic brain injury characteristics with prospective suicide attempt among deployed US Army soldiers. J Head Trauma Rehabil. 2020;35(1):14–26.
Teasdale G, Jennett B. Assessment and prognosis of coma after head injury. Acta Neurochir (Wien). 1976;34(1–4):45–55.
Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–613.
Corrigan JD, Bogner J. Initial reliability and validity of the Ohio State University TBI Identification Method. J Head Trauma Rehabil. 2007;22(6):318–329.
Bush K, Kivlahan DR, McDonell MB, Fihn SD, Bradley KA. The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test. Arch Intern Med. 1998;158(16):1789–1795.
King NS, Crawford S, Wenden FJ, Moss NE, Wade DT. The Rivermead Post Concussion Symptoms Questionnaire: a measure of symptoms commonly experienced after head injury and its reliability. J Neurol. 1995;242(9):587–592.
Agtarap S, Kramer MD, Campbell-Sills L, et al. Invariance of the bifactor structure of mild traumatic brain injury (mTBI) symptoms on the Rivermead Postconcussion Symptoms Questionnaire across time, demographic characteristics, and clinical groups: A TRACK-TBI Study [published online ahead of print April 24, 2020]. Assessment. doi:10.1177/1073191120913941.
Derogatis L. BSI-18: Brief Symptom Inventory 18 Administration, Scoring, and Procedures Manual. Minneapolis, MN: NCS Pearson Inc; 2001.
McCaffrey DF, Ridgeway G, Morral AR. Propensity score estimation with boosted regression for evaluating causal effects in observational studies. Psychol Methods. 2004;9(4):403–425.
R: A language and environment for statistical computing [computer program]. Vienna, Austria: R Foundation for Statistical Computing; 2016.
Klonsky ED, May AM, Saffer BY. Suicide, suicide attempts, and suicidal ideation. Annu Rev Clin Psychol. 2016;12:307–330.
Nolan A, Hennessy E, Krukowski K, et al. Repeated mild head injury leads to wide-ranging deficits in higher-order cognitive functions associated with the prefrontal cortex. J Neurotrauma. 2018;35(20):2425–2434.
Qaseem A, Barry MJ, Kansagara D, Clinical guidelines committee of the American College of Physicians. Nonpharmacologic versus pharmacologic treatment of adult patients with major depressive disorder: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2016;164(5):350–359.
Mann JJ, Apter A, Bertolote J, et al. Suicide prevention strategies: a systematic review. JAMA. 2005;294(16):2064–2074.
Kesinger MR, Juengst SB, Bertisch H, et al. Acute trauma factor associations with suicidality across the first 5 years after traumatic brain injury. Arch Phys Med Rehabil. 2016;97(8):1301–1308.
Kessler RC, Berglund P, Borges G, Nock M, Wang PS. Trends in suicide ideation, plans, gestures, and attempts in the United States, 1990-1992 to 2001-2003. JAMA. 2005;293(20):2487–2495.
Substance Abuse and Mental Health Services Administration. Key Substance Use and Mental Health Indicators in the United States: Results From the 2018 National Survey on Drug Use and Health (HHS Publication No. PEP19-5068, NSDUH Series H-54). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration; 2019.
Glenn CR, Nock MK. Improving the short-term prediction of suicidal behavior. Am J Prev Med. 2014;47(3 suppl 2):S176–S180.
Nock MK, Borges G, Bromet EJ, Cha CB, Kessler RC, Lee S. Suicide and suicidal behavior. Epidemiol Rev. 2008;30:133–154.