Evolving models for assembling and shaping clathrin-coated pits.
Journal
The Journal of cell biology
ISSN: 1540-8140
Titre abrégé: J Cell Biol
Pays: United States
ID NLM: 0375356
Informations de publication
Date de publication:
07 09 2020
07 09 2020
Historique:
received:
05
06
2020
revised:
13
07
2020
accepted:
13
07
2020
entrez:
10
8
2020
pubmed:
10
8
2020
medline:
23
3
2021
Statut:
ppublish
Résumé
Clathrin-mediated endocytosis occurs via the assembly of clathrin-coated pits (CCPs) that invaginate and pinch off to form clathrin-coated vesicles (CCVs). It is well known that adaptor protein 2 (AP2) complexes trigger clathrin assembly on the plasma membrane, and biochemical and structural studies have revealed the nature of these interactions. Numerous endocytic accessory proteins collaborate with clathrin and AP2 to drive CCV formation. However, many questions remain as to the molecular events involved in CCP initiation, stabilization, and curvature generation. Indeed, a plethora of recent evidence derived from cell perturbation, correlative light and EM tomography, live-cell imaging, modeling, and high-resolution structural analyses has revealed more complexity and promiscuity in the protein interactions driving CCP maturation than anticipated. After briefly reviewing the evidence supporting prevailing models, we integrate these new lines of evidence to develop a more dynamic and flexible model for how redundant, dynamic, and competing protein interactions can drive endocytic CCV formation and suggest new approaches to test emerging models.
Identifiants
pubmed: 32770195
pii: 152007
doi: 10.1083/jcb.202005126
pmc: PMC7480099
pii:
doi:
Substances chimiques
Adaptor Protein Complex 2
0
Clathrin
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM042455
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM073165
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH061345
Pays : United States
Organisme : NIMH NIH HHS
ID : R37 MH061345
Pays : United States
Informations de copyright
© 2020 Chen and Schmid.
Références
J Cell Sci. 2018 Sep 3;131(17):
pubmed: 30177505
Cell Rep. 2019 Jun 4;27(10):3049-3061.e6
pubmed: 31167147
Nat Commun. 2019 Oct 1;10(1):4462
pubmed: 31575863
Nature. 2012 Mar 07;483(7389):336-40
pubmed: 22398450
Biol Open. 2014 Apr 04;3(5):326-31
pubmed: 24705016
J Mol Biol. 2010 Nov 26;404(2):274-90
pubmed: 20875424
EMBO J. 2004 Nov 10;23(22):4371-83
pubmed: 15496985
Traffic. 2011 Nov;12(11):1620-33
pubmed: 21762456
Phys Rev E. 2016 Dec;94(6-1):062404
pubmed: 28085411
Trends Cell Biol. 2019 Mar;29(3):241-256
pubmed: 30598298
EMBO J. 1998 Sep 1;17(17):4943-53
pubmed: 9724631
Science. 2015 Jun 19;348(6241):1369-72
pubmed: 26089517
Traffic. 2012 Apr;13(4):511-9
pubmed: 22239657
EMBO J. 2015 Aug 13;34(16):2132-46
pubmed: 26139537
Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7189-94
pubmed: 26015579
Nat Rev Mol Cell Biol. 2011 Jul 22;12(8):517-33
pubmed: 21779028
J Cell Biol. 1969 Jul;42(1):202-20
pubmed: 4182372
Chembiochem. 2003 Jan 3;4(1):14-25
pubmed: 12512072
J Phys D Appl Phys. 2018 Aug;51(34):
pubmed: 30655651
Cold Spring Harb Perspect Biol. 2014 Aug 28;6(12):a017038
pubmed: 25167858
J Biol Chem. 2008 Feb 22;283(8):5099-109
pubmed: 17986441
Mol Biol Cell. 2006 Dec;17(12):5298-308
pubmed: 17035630
J Mol Biol. 2018 Nov 2;430(23):4636-4649
pubmed: 30099026
Cold Spring Harb Perspect Biol. 2013 Nov 01;5(11):a016790
pubmed: 24186068
J Cell Biol. 2010 Mar 22;188(6):919-33
pubmed: 20231386
Nat Cell Biol. 2012 Apr 22;14(6):634-9
pubmed: 22522172
Sci Adv. 2020 Jul 22;6(30):eaba8397
pubmed: 32743076
Cell. 2012 Aug 3;150(3):495-507
pubmed: 22863004
Nat Rev Mol Cell Biol. 2017 May;18(5):285-298
pubmed: 28225081
Nat Rev Mol Cell Biol. 2018 May;19(5):313-326
pubmed: 29410531
Trends Cell Biol. 1996 Mar;6(3):85-9
pubmed: 15157483
Nat Commun. 2015 Jul 24;6:7875
pubmed: 26204806
PLoS Biol. 2013 Oct;11(10):e1001670
pubmed: 24130457
Nat Cell Biol. 1999 May;1(1):33-9
pubmed: 10559861
J Cell Biol. 1983 Nov;97(5 Pt 1):1339-47
pubmed: 6138359
Nature. 2013 Jul 11;499(7457):233-7
pubmed: 23823722
Nat Chem. 2017 Nov;9(11):1118-1125
pubmed: 29064502
Annu Rev Cell Dev Biol. 2011;27:79-105
pubmed: 21599493
Elife. 2020 Apr 30;9:
pubmed: 32352376
Dev Cell. 2012 Sep 11;23(3):519-32
pubmed: 22940114
Annu Rev Biochem. 2018 Jun 20;87:871-896
pubmed: 29661000
PLoS Biol. 2009 Mar 17;7(3):e57
pubmed: 19296720
PLoS Biol. 2011 Mar;9(3):e1000604
pubmed: 21445324
Nat Cell Biol. 2017 Apr;19(4):352-361
pubmed: 28346440
EMBO J. 1986 Mar;5(3):529-34
pubmed: 3635476
Dev Cell. 2015 Apr 20;33(2):163-75
pubmed: 25898166
J Cell Biol. 1964 Feb;20:313-32
pubmed: 14126875
EMBO J. 2016 Nov 2;35(21):2270-2284
pubmed: 27670760
PLoS Biol. 2018 May 3;16(5):e2004786
pubmed: 29723197
Mol Biol Cell. 2005 Apr;16(4):1769-76
pubmed: 15689492
Nature. 2004 Dec 2;432(7017):649-53
pubmed: 15502813
J Biol Chem. 1995 Dec 29;270(52):31083-90
pubmed: 8537368
Science. 2017 Sep 22;357(6357):
pubmed: 28935776
Nature. 2010 Mar 11;464(7286):243-9
pubmed: 20190736
J Mol Biol. 1975 Sep 5;97(1):93-8
pubmed: 1177317
Dev Cell. 2005 Nov;9(5):581-92
pubmed: 16256734
PLoS Biol. 2006 Sep;4(9):e262
pubmed: 16903783
J Cell Biol. 2017 Sep 4;216(9):2623-2632
pubmed: 28674108
J Cell Biol. 1973 May;57(2):315-44
pubmed: 4348786
Nat Cell Biol. 2013 Jan;15(1):50-60
pubmed: 23263279
Nat Commun. 2018 Oct 8;9(1):4152
pubmed: 30297718
Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1096-100
pubmed: 10655490
J Cell Biol. 2001 Oct 15;155(2):291-300
pubmed: 11604424
Nature. 1981 Jan 29;289(5796):420-2
pubmed: 7464911
J Cell Biol. 2020 Sep 7;219(9):
pubmed: 32520988
J Cell Biol. 2017 Dec 4;216(12):4351-4365
pubmed: 28954824
J Cell Biol. 2003 Sep 1;162(5):909-18
pubmed: 12952941
Cell. 2011 Aug 5;146(3):471-84
pubmed: 21816279
Elife. 2014 Oct 16;3:
pubmed: 25321392
Nat Cell Biol. 2011 Aug 14;13(9):1124-31
pubmed: 21841790
Proc Natl Acad Sci U S A. 1976 Apr;73(4):1255-9
pubmed: 1063406
Traffic. 2005 Oct;6(10):918-29
pubmed: 16138905
Cell. 2004 Sep 3;118(5):591-605
pubmed: 15339664
Science. 2014 Jul 25;345(6195):459-63
pubmed: 25061211
Nat Commun. 2018 Mar 16;9(1):1109
pubmed: 29549258
J Cell Biol. 2017 Nov 6;216(11):3745-3765
pubmed: 28923975
Nature. 2007 Aug 23;448(7156):883-8
pubmed: 17713526
J Cell Biol. 2010 Dec 27;191(7):1381-93
pubmed: 21187331
Annu Rev Cell Dev Biol. 2004;20:153-91
pubmed: 15473838
Cell Biochem Biophys. 2004;41(2):295-318
pubmed: 15475615
PLoS Biol. 2018 Apr 18;16(4):e2005377
pubmed: 29668686
J Mol Med (Berl). 2010 Apr;88(4):339-50
pubmed: 20127478
J Cell Biol. 2019 Feb 4;218(2):664-682
pubmed: 30504247
Structure. 2002 Jun;10(6):797-809
pubmed: 12057195
Cell. 2005 Oct 21;123(2):305-20
pubmed: 16239147
Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3258-E3267
pubmed: 28373566
Science. 2001 Feb 9;291(5506):1051-5
pubmed: 11161218
FEBS Lett. 1997 Aug 18;413(2):319-22
pubmed: 9280305
Cell. 2018 Aug 9;174(4):884-896.e17
pubmed: 30057119
Sci Rep. 2015 May 06;5:9994
pubmed: 25944393
Traffic. 2012 Jan;13(1):70-81
pubmed: 21939487
EMBO J. 1984 Sep;3(9):1951-7
pubmed: 6149117
Mol Biol Cell. 2020 Aug 15;31(18):2035-2047
pubmed: 32579424
J Cell Biol. 2020 Mar 2;219(3):
pubmed: 31962345
Cell. 1983 May;33(1):273-85
pubmed: 6147196
Dev Cell. 2013 Aug 12;26(3):279-91
pubmed: 23891661
Nature. 2002 Sep 26;419(6905):361-6
pubmed: 12353027
J Cell Sci. 2001 Mar;114(Pt 6):1041-52
pubmed: 11228149
J Cell Biol. 2017 Jan 2;216(1):167-179
pubmed: 28003333
Structure. 2010 Oct 13;18(10):1233-43
pubmed: 20947012
Mol Biol Cell. 2009 Jul;20(14):3401-13
pubmed: 19458198
Mol Cancer. 2013 Jan 17;12:4
pubmed: 23327284
Cell. 2010 Jun 25;141(7):1220-9
pubmed: 20603002
Traffic. 2011 Jul;12(7):815-25
pubmed: 21447041
Sci Adv. 2020 Jul 22;6(30):eaba8381
pubmed: 32743075
J Cell Biol. 1980 Mar;84(3):560-83
pubmed: 6987244
J Cell Biol. 2019 Oct 7;218(10):3200-3211
pubmed: 31451612
Nat Commun. 2018 Jan 29;9(1):419
pubmed: 29379015
J Cell Biol. 1986 Dec;103(6 Pt 2):2619-27
pubmed: 2878930
Dev Cell. 2006 Mar;10(3):329-42
pubmed: 16516836
Dev Cell. 2019 Aug 19;50(4):436-446.e5
pubmed: 31353312
Proc Natl Acad Sci U S A. 1978 Sep;75(9):4394-8
pubmed: 30086
Trends Cell Biol. 2009 Nov;19(11):596-605
pubmed: 19836955
Traffic. 2017 Jan;18(1):44-57
pubmed: 27813245
Dev Cell. 2016 Jun 6;37(5):428-43
pubmed: 27237791