Assessing the Desmoid-Type Fibromatosis Patients' Voice: Comparison of Health-Related Quality of Life Experiences from Patients of Two Countries.


Journal

Sarcoma
ISSN: 1357-714X
Titre abrégé: Sarcoma
Pays: Egypt
ID NLM: 9709257

Informations de publication

Date de publication:
2020
Historique:
received: 04 05 2020
revised: 27 06 2020
accepted: 29 06 2020
entrez: 11 8 2020
pubmed: 11 8 2020
medline: 11 8 2020
Statut: epublish

Résumé

Desmoid-type fibromatosis (DTF) is a rare, nonmetastasising soft tissue tumour. Symptoms, unpredictable growth, lack of definitive treatments, and the chronic character of the disease can significantly impact health-related quality of life (HRQoL). We aimed at identifying the most important HRQoL issues according to DTF patients in two countries, in order to devise a specific HRQoL questionnaire for this patient group. DTF patients and healthcare providers (HCPs) from the Netherlands and the United Kingdom individually ranked 124 issues regarding diagnosis, treatment, follow-up, recurrence, living with DTF, healthcare, and supportive care experiences, according to their relevance. Descriptive statistics were used to calculate priority scores. The most highly ranked issues by patients ( This study identified the most relevant issues for DTF patients, which should be included in a DTF-specific HRQoL questionnaire. Additionally, we identified differences in priority scores between British and Dutch participating patients. Field testing in a large, international cohort is needed to confirm these findings and to devise a comprehensive and specific HRQoL questionnaire for DTF patients.

Identifiants

pubmed: 32774131
doi: 10.1155/2020/2141939
pmc: PMC7399762
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2141939

Informations de copyright

Copyright © 2020 Milea J. M. Timbergen et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Milea J M Timbergen (MJM)

Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.

Winette T A van der Graaf (WTA)

Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands.
Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, Netherlands.

Dirk J Grünhagen (DJ)

Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.

Eugenie Younger (E)

Sarcoma Unit, Royal Marsden NHS Foundation Trust, London, UK.
Division of Clinical Studies, Institute of Cancer Research, Royal Marsden NHS Foundation Trust, London, UK.

Stefan Sleijfer (S)

Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.

Alison Dunlop (A)

Sarcoma Unit, Royal Marsden NHS Foundation Trust, London, UK.

Lucy Dean (L)

Sarcoma Unit, Royal Marsden NHS Foundation Trust, London, UK.

Cornelis Verhoef (C)

Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.

Lonneke V van de Poll-Franse (LV)

Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, Netherlands.
Department of Medical and Clinical Psychology, Tilburg University, Netherlands.
Department of Research, Netherlands Comprehensive Cancer Organisation (IKNL), Eindhoven, Netherlands.

Olga Husson (O)

Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands.
Sarcoma Unit, Royal Marsden NHS Foundation Trust, London, UK.
Division of Clinical Studies, Institute of Cancer Research, Royal Marsden NHS Foundation Trust, London, UK.
Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, Netherlands.

Classifications MeSH