Re-establishing indwelling pleural catheter patency with alteplase after failure of streptokinase.
Alteplase
blocked
indwelling pleural catheter
malignant pleural effusion
streptokinase
Journal
Respirology case reports
ISSN: 2051-3380
Titre abrégé: Respirol Case Rep
Pays: United States
ID NLM: 101631052
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
01
07
2020
revised:
15
07
2020
accepted:
16
07
2020
entrez:
11
8
2020
pubmed:
11
8
2020
medline:
11
8
2020
Statut:
epublish
Résumé
Indwelling pleural catheter (IPC) has revolutionized the management of malignant pleural effusion (MPE). IPC is relatively safe, although complications can occur. We report a 53-year-old woman with stage IVA lung adenocarcinoma and recurrent MPE. Two months post insertion, the IPC was blocked with residual effusion and presence of new loculations. Attempts to restore patency with six doses of intrapleural (IP) streptokinase failed. She was referred to our centre for further management. We used a single dose of 2.5 mg IP alteplase which was successful in establishing patency of the IPC and draining the effusion. This case highlights the safety and efficacy of IP alteplase via IPC following a failed instillation of streptokinase.
Identifiants
pubmed: 32774860
doi: 10.1002/rcr2.639
pii: RCR2639
pmc: PMC7406907
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e00639Informations de copyright
© 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.
Références
Chest. 2003 Feb;123(2):432-5
pubmed: 12576362
Am J Respir Crit Care Med. 2000 Nov;162(5):1987-2001
pubmed: 11069845
Ther Adv Respir Dis. 2018 Jan-Dec;12:1753466618785098
pubmed: 29952251
Chest. 2020 Jun 17;:
pubmed: 32561437
BMJ Open Respir Res. 2016 Feb 05;3(1):e000123
pubmed: 26870384