Use of Antipsychotic Drugs During Pregnancy.
antipsychotic
breastfeeding
lactation
neuroleptic
pregnancy
Journal
Current treatment options in psychiatry
ISSN: 2196-3061
Titre abrégé: Curr Treat Options Psychiatry
Pays: Switzerland
ID NLM: 101626387
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
entrez:
11
8
2020
pubmed:
1
3
2019
medline:
1
3
2019
Statut:
ppublish
Résumé
Antipsychotics are frequently prescribed to women of childbearing age and are increasingly prescribed during pregnancy. A small, but growing, body of research on implications for pregnancy and infant outcomes is available to inform the risks and benefits of in utero exposure to antipsychotics. This review examines the existing published research on the use of common typical and atypical antipsychotics in pregnancy and the implications for pregnancy and infant outcomes. The majority of studies do not show associations with major malformations and antipsychotic use in pregnancy, with the possible exception of risperidone. There is concern that atypical antipsychotics may be associated with gestational diabetes. Metabolic changes during pregnancy may necessitate dose adjustments. In general, it is recommended that women who need to take an antipsychotic during pregnancy continue the antipsychotic that has been most effective for symptom remission. Further study on risperidone is needed to better understand its association with malformations and it is not considered a first-line agent for use during pregnancy.
Identifiants
pubmed: 32775146
doi: 10.1007/s40501-019-0165-5
pmc: PMC7410162
mid: NIHMS1519961
doi:
Types de publication
Journal Article
Langues
eng
Pagination
17-31Subventions
Organisme : NICHD NIH HHS
ID : K23 HD087529
Pays : United States
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