Clinical characteristics of patients with COVID-19 presenting with gastrointestinal symptoms as initial symptoms: Retrospective case series.
COVID-19
Gastrointestinal symptoms
Hospitalization
Initial symptoms
Viral transmission
Journal
World journal of clinical cases
ISSN: 2307-8960
Titre abrégé: World J Clin Cases
Pays: United States
ID NLM: 101618806
Informations de publication
Date de publication:
26 Jul 2020
26 Jul 2020
Historique:
received:
21
05
2020
revised:
14
06
2020
accepted:
01
07
2020
entrez:
11
8
2020
pubmed:
11
8
2020
medline:
11
8
2020
Statut:
ppublish
Résumé
A large number of pneumonia cases due to coronavirus disease 2019 (COVID-19) have been first reported in China. Meanwhile, the virus is sweeping all around the world and has infected millions of people. Fever and pulmonary symptoms have been noticed as major and early signs of infection, whereas gastrointestinal symptoms were also observed in a significant portion of patients. The clinical investigation of disease onset was underestimated, especially due to the neglection of cases presenting with gastrointestinal symptoms. To characterize the clinical features of coronavirus-infected patients with gastrointestinal symptoms as initial symptoms. This is a retrospective, single-center case series of the general consecutive hospitalized patients with confirmed COVID-19 at Wuhan Union Hospital from February 2, 2020 to February 13, 2020. According to their initial symptoms, these patients were classified into two groups. Patients in group one presented with pulmonary symptoms (PS) as initial symptoms, and group two presented with gastrointestinal symptoms (GS). Epidemiological, demographic, clinical, laboratory, and treatment data were collected for analysis. Among the 50 patients recruited, no patient has been admitted to intensive care units, and no patient died during the study. The duration of hospitalization was longer in the GS group than in the PS group (12.13 COVID-19 patients presenting with gastrointestinal symptoms as initial symptoms need more days of viral shedding and hospitalization than the patients presenting with pulmonary symptoms.
Sections du résumé
BACKGROUND
BACKGROUND
A large number of pneumonia cases due to coronavirus disease 2019 (COVID-19) have been first reported in China. Meanwhile, the virus is sweeping all around the world and has infected millions of people. Fever and pulmonary symptoms have been noticed as major and early signs of infection, whereas gastrointestinal symptoms were also observed in a significant portion of patients. The clinical investigation of disease onset was underestimated, especially due to the neglection of cases presenting with gastrointestinal symptoms.
AIM
OBJECTIVE
To characterize the clinical features of coronavirus-infected patients with gastrointestinal symptoms as initial symptoms.
METHODS
METHODS
This is a retrospective, single-center case series of the general consecutive hospitalized patients with confirmed COVID-19 at Wuhan Union Hospital from February 2, 2020 to February 13, 2020. According to their initial symptoms, these patients were classified into two groups. Patients in group one presented with pulmonary symptoms (PS) as initial symptoms, and group two presented with gastrointestinal symptoms (GS). Epidemiological, demographic, clinical, laboratory, and treatment data were collected for analysis.
RESULTS
RESULTS
Among the 50 patients recruited, no patient has been admitted to intensive care units, and no patient died during the study. The duration of hospitalization was longer in the GS group than in the PS group (12.13
CONCLUSION
CONCLUSIONS
COVID-19 patients presenting with gastrointestinal symptoms as initial symptoms need more days of viral shedding and hospitalization than the patients presenting with pulmonary symptoms.
Identifiants
pubmed: 32775377
doi: 10.12998/wjcc.v8.i14.2950
pmc: PMC7385610
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2950-2958Informations de copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Références
World J Clin Cases. 2020 Apr 26;8(8):1343-1349
pubmed: 32368528
J Med Virol. 2020 Apr;92(4):433-440
pubmed: 31967321
Gut. 2020 Jun;69(6):1141-1143
pubmed: 32102928
SN Compr Clin Med. 2020 May 12;:1-4
pubmed: 32399516
BMJ. 2020 Mar 26;368:m1091
pubmed: 32217556
JAMA. 2020 Feb 7;:
pubmed: 32031570
BMJ. 2020 Mar 5;368:m800
pubmed: 32144127
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Aliment Pharmacol Ther. 2020 May;51(9):843-851
pubmed: 32222988
World J Clin Cases. 2020 Apr 26;8(8):1385-1390
pubmed: 32368531
Front Med. 2020 Apr;14(2):126-135
pubmed: 32240462
Chin Med J (Engl). 2020 May 5;133(9):1080-1086
pubmed: 32149773
JAMA Cardiol. 2020 Mar 27;:
pubmed: 32219356
Emerg Microbes Infect. 2020 Dec;9(1):727-732
pubmed: 32196410
Lancet. 2020 Feb 15;395(10223):470-473
pubmed: 31986257
Mil Med Res. 2020 Mar 13;7(1):11
pubmed: 32169119
J Dig Dis. 2020 Mar;21(3):125-126
pubmed: 32096611
Gut. 2020 Jun;69(6):997-1001
pubmed: 32241899
World J Clin Cases. 2020 May 6;8(9):1705-1712
pubmed: 32420305
Aging Dis. 2020 Mar 9;11(2):216-228
pubmed: 32257537
Cell Biosci. 2020 Mar 16;10:40
pubmed: 32190290
Gastroenterology. 2020 Jun;158(8):2294-2297
pubmed: 32199880
JAMA. 2020 Jan 23;:
pubmed: 31971553