Orbital myeloid sarcoma (chloroma): Report of 2 cases and literature review.
Acute myeloid leukemia
Magnetic resonance imaging
Myeloid sarcoma
Orbital pathology
Pediatric tumor
Journal
American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
05
05
2020
accepted:
28
06
2020
entrez:
11
8
2020
pubmed:
11
8
2020
medline:
11
8
2020
Statut:
epublish
Résumé
Myeloid sarcoma (MS) of the orbit is an uncommon condition in occurring in children, generally coupled to myeloproliferative neoplasms. We describe two rare cases of orbital MS in young boys with aggressive local symptoms but without evidence of acute myeloid leukemia (AML), both patients underwent orbitotomy for gross-tumor resection and biopsy. At follow up, there was no evidence of recurrence nor evolution of the myeloproliferative neoplasms clinically and by radiological and laboratory work-up. We also provide a detailed description of the magnetic resonance imaging presentation, with an extensive pathological analysis correlation. A comprehensive revision of the literature on isolated orbital MS was carried out with particular emphasis on clues for differential diagnosis and treatment options, stressing the need to consider MS even in the absence of sign and symptoms of an underlying myeloproliferative disorders.
Identifiants
pubmed: 32775766
doi: 10.1016/j.ajoc.2020.100806
pii: S2451-9936(20)30139-0
pii: 100806
pmc: PMC7397738
doi:
Types de publication
Case Reports
Langues
eng
Pagination
100806Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
The following authors have no financial disclosures (MP, MA, CR, HA, AM, SE, RM, MM, AE, LR, RC, DS).
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