Bifunctional Peptide-Polymer Conjugate-Based Fibers via a One-Pot Tandem Disulfide Reduction Coupled to a Thio-Bromo "Click" Reaction.


Journal

ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658

Informations de publication

Date de publication:
04 Aug 2020
Historique:
received: 18 05 2020
accepted: 01 07 2020
entrez: 11 8 2020
pubmed: 11 8 2020
medline: 11 8 2020
Statut: epublish

Résumé

In view of the potential applications of fibers in material sciences and biomedicine, an effective synthetic strategy is described to construct peptide-based bifunctional polymeric conjugates for supramolecular self-association in solution. A direct coupling method of an α-acyl-brominated peptide Phe-Phe-Phe-Phe (FFFF) with a disulfide-bridged polymeric scaffold of poly(ethylene glycol) (PEG) (

Identifiants

pubmed: 32775904
doi: 10.1021/acsomega.0c02326
pmc: PMC7408259
doi:

Types de publication

Journal Article

Langues

eng

Pagination

19020-19028

Informations de copyright

Copyright © 2020 American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Sonu Kumar (S)

Macromolecular Chemistry, Faculty of Natural Science II (Chemistry, Physics and Mathematics), Institute of Chemistry, Martin Luther University Halle-Wittenberg, Von-Danckelmann-Platz 4, Halle (Saale) D-06120, Germany.
Department of Applied Sciences (Chemistry), Punjab Engineering College (Deemed to be University), Sector 12, Chandigarh 160012, India.

Gerd Hause (G)

Biocenter, Martin Luther University Halle-Wittenberg, Weinbergweg 22, Halle (Saale) D-06120, Germany.

Wolfgang H Binder (WH)

Macromolecular Chemistry, Faculty of Natural Science II (Chemistry, Physics and Mathematics), Institute of Chemistry, Martin Luther University Halle-Wittenberg, Von-Danckelmann-Platz 4, Halle (Saale) D-06120, Germany.

Classifications MeSH