Contact sensitization in metalworkers: Data from the information network of departments of dermatology (IVDK), 2010-2018.
Adult
Dermatitis, Allergic Contact
/ diagnosis
Dermatitis, Occupational
/ diagnosis
Environmental Monitoring
/ methods
Female
Germany
Hand Dermatoses
/ chemically induced
Humans
Industrial Oils
/ adverse effects
Male
Metallurgy
Middle Aged
Occupational Exposure
/ adverse effects
Patch Tests
Retrospective Studies
Risk Factors
colophonium
formaldehyde releaser
iodopropynyl butylcarbamate
mechanics
metalworkers
metalworking fluid
monoethanolamine
occupational dermatitis
Journal
Contact dermatitis
ISSN: 1600-0536
Titre abrégé: Contact Dermatitis
Pays: England
ID NLM: 7604950
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
26
05
2020
revised:
05
08
2020
accepted:
06
08
2020
pubmed:
11
8
2020
medline:
7
8
2021
entrez:
11
8
2020
Statut:
ppublish
Résumé
Metalworkers are exposed to a variety of contact allergens by handling tools, metals, metalworking fluids (MWFs), oils and greases, rubber materials, and so on. Most large-scale reports on contact allergy due to MWFs are more than 10-years-old, and there are only few studies on contact allergy in mechanics and other metal workers not exposed to MWFs. To describe a current spectrum of contact sensitization in metalworkers with occupational dermatitis (OD). Retrospective analysis of patch test data collected by the Information Network of Departments of Dermatology (IVDK; 2010-2018), stratifying for 804 cutting metalworkers, 2197 mechanics, and 355 other metalworkers. Cutting metalworkers were most frequently sensitized to monoethanolamine (12.6%), colophonium/abietic acid (11.4%) and formaldehyde releasers (up to 8.5%) from the MWF series, and formaldehyde (4.6%) and iodopropynyl butylcarbamate (4.6%) from the baseline series. Sensitization among mechanics and other metalworkers indicates possible occupational exposure to MWFs, glues, and resins, although this may not be expected from their job titles. The spectrum of MWF contact allergens remained largely unchanged during the last years. Taking a comprehensive occupational history is indispensable in order to not miss relevant allergen exposures.
Sections du résumé
BACKGROUND
BACKGROUND
Metalworkers are exposed to a variety of contact allergens by handling tools, metals, metalworking fluids (MWFs), oils and greases, rubber materials, and so on. Most large-scale reports on contact allergy due to MWFs are more than 10-years-old, and there are only few studies on contact allergy in mechanics and other metal workers not exposed to MWFs.
OBJECTIVES
OBJECTIVE
To describe a current spectrum of contact sensitization in metalworkers with occupational dermatitis (OD).
PATIENTS AND METHODS
METHODS
Retrospective analysis of patch test data collected by the Information Network of Departments of Dermatology (IVDK; 2010-2018), stratifying for 804 cutting metalworkers, 2197 mechanics, and 355 other metalworkers.
RESULTS
RESULTS
Cutting metalworkers were most frequently sensitized to monoethanolamine (12.6%), colophonium/abietic acid (11.4%) and formaldehyde releasers (up to 8.5%) from the MWF series, and formaldehyde (4.6%) and iodopropynyl butylcarbamate (4.6%) from the baseline series. Sensitization among mechanics and other metalworkers indicates possible occupational exposure to MWFs, glues, and resins, although this may not be expected from their job titles.
CONCLUSIONS
CONCLUSIONS
The spectrum of MWF contact allergens remained largely unchanged during the last years. Taking a comprehensive occupational history is indispensable in order to not miss relevant allergen exposures.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
487-496Subventions
Organisme : This work was part of the OCCUDERM project, which was funded by the Volkswagen Foundation (Niedersächsisches Vorab ZN2778).
Informations de copyright
© 2020 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.
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