Increased frequency of sleep problems in children and adolescents with familial Mediterranean fever: The role of anxiety and depression.
Adolescent
Anxiety
/ epidemiology
Child
Cross-Sectional Studies
Depression
/ epidemiology
Familial Mediterranean Fever
/ complications
Female
Follow-Up Studies
Health Status
Humans
Incidence
Male
Quality of Life
Retrospective Studies
Severity of Illness Index
Sleep
/ physiology
Sleep Wake Disorders
/ epidemiology
Surveys and Questionnaires
Turkey
/ epidemiology
adolescents
anxiety
children
depression
familial Mediterranean fever
sleep habits
Journal
International journal of rheumatic diseases
ISSN: 1756-185X
Titre abrégé: Int J Rheum Dis
Pays: England
ID NLM: 101474930
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
10
04
2020
revised:
27
06
2020
accepted:
20
07
2020
pubmed:
11
8
2020
medline:
3
11
2021
entrez:
11
8
2020
Statut:
ppublish
Résumé
Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory disease. The main goal of our study is to compare sleep habits, depression and anxiety of patients with FMF to healthy children and to determine the influence of disease-related factors on sleep habits and psychiatric symptoms. In total, 323 child and adolescent patients with FMF and 260 healthy peers as a control group were included in this study. Questionnaires were used to evaluate sleep habits, psychological status of children and adolescents with and without FMF. While there was not a significant difference in terms of age, gender, depression and anxiety scores (P > 0.05); patients with FMF had significantly higher total sleeping score (45.69 ± 7.70 vs 43.31 ± 7.77; P = 0.001). Depression and anxiety scores of patients with FMF who have been experiencing sleep problems were found to be dramatically higher compared to those FMF patients without sleep problems (7.70 ± 5.56 vs 4.59 ± 3.97; P = 0.001; 35.46 ± 18.57 vs 25.22 ± 14.12; P = 0.001; respectively). Patients with FMF who had a disease attack last month had remarkably higher depression, anxiety and sleeping scores compared to those who did not. When FMF patients were compared in terms of exertional leg pain, increased acute phase reactant levels, comorbidity and mutation types, there was not a significant difference for depression, anxiety and sleeping scores. Children and adolescents with FMF experience more sleeping problems compared to healthy children and in presence of sleeping disorders, psychiatric symptoms are seen more frequently. Therefore, evaluation of psychopathology is important if youth with FMF have sleep problems.
Identifiants
pubmed: 32776695
doi: 10.1111/1756-185X.13941
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1396-1403Informations de copyright
© 2020 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.
Références
Adrovic A, Sahin S, Barut K, Kasapcopur O. Familial Mediterranean fever and periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: shared features and main differences. Rheumatol Int. 2019;39(1):29-36.
Ozen S, Bilginer Y. A clinical guide to autoinflammatory diseases: familial Mediterranean fever and next-of-kin. Nat Rev Rheumatol. 2014;10(3):135-147.
Barut K, Sahin S, Adrovic A, et al. Familial Mediterranean fever in childhood: a single-center experience. Rheumatol Int. 2018;38(1):67-74.
Livneh A, Langevitz P, Zemer D, et al. Criteria for the diagnosis of familial Mediterranean fever. Arthritis Rheum. 1997;40:1879-1885.
De Benedetti F, Gattorno M, Anton J, et al. Canakinumab for the treatment of autoinflammatory recurrent fever syndromes. N Engl J Med. 2018;378(20):1908-1919.
Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci. 2008;9(1):46-56.
Hart BL. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev. 1988;12(2):123-137.
Amin R, Bean J, Burklow K, Jeffries J. The relationship between sleep disturbance and pulmonary function in stable pediatric cystic fibrosis patients. Chest. 2005;128(3):1357-1363.
Parisi P, Bruni O, Pia Villa M, et al. The relationship between sleep and epilepsy: the effect on cognitive functioning in children. Dev Med Child Neurol. 2010;52(9):805-810.
Cakirbay H, Bilici M, Kavakcı Ö, Cebi A, Guler M, Tan U. Sleep quality and immune functions in rheumatoid arthritis patients with and without major depression. Int J Neurosci. 2004;114(2):245-256.
Bourguignon C, Labyak SE, Taibi D. Investigating sleep disturbances in adults with rheumatoid arthritis. Holist Nurs Pract. 2003;17(5):241-249.
Ward TM, Sonney J, Ringold S, Stockfish S, Wallace CA, Landis CA. Sleep disturbances and behavior problems in children with and without arthritis. J Pediatr Nurs. 2014;29(4):321-328.
Yildiz M, Adrovic A, Taşdemir E, et al. Evaluation of coexisting diseases in children with familial Mediterranean fever. Rheumatol Int. 2019;40(1):57-64.
Makay B, Kiliçaslan SK, Anik A, et al. Assessment of sleep problems in children with familial Mediterranean fever. Int J Rheum Dis. 2014;20(12):2106-2112.
Fidan T, Ertekin V, Sürücü İ. Psychological correlates of child and adolescents with familial Mediterranean fever. Rheumatol Int. 2011;31(6):837-838.
Makay B, Emiroğlu N, Ünsal E. Depression and anxiety in children and adolescents with familial Mediterranean fever. Clin Rheumatol. 2010;29(4):375-379.
Özer S, Bozkurt H, Yılmaz R, Sönmezgöz E, Bütün I. Evaluation of executive functions in children and adolescents with familial Mediterranean fever. Child Neuropsychol. 2015;23(3):332-342.
Yalçınkaya F, Özen S, Özçakar ZB, et al. A new set of criteria for the diagnosis of familial Mediterranean fever in childhood. Rheumatology. 2009;48(4):395-398.
Pras E, Livneh A, Balow JE Jr, et al. Clinical differences between North African and Iraqi Jews with familial Mediterranean fever. Am J Med Genet. 1998;75:216-219.
Kallinich T, Haffner D, Niehues T, et al. Colchicine use in children and adolescents with familial Mediterranean fever: literature review and consensus statement. Pediatrics. 2007;119(2):e474-e483.
Chorpita BF, Yim L, Moffitt C, Umemoto LA, Francis SE. Assessment of symptoms of DSM-IV anxiety and depression in children: a revised child anxiety and depression scale. Behav Res Ther. 2000;38(8):835-855.
Gormez V, Kilincaslan A, Orengul AC, et al. Psychometric properties of the Turkish version of the Revise Child Anxiety and Depression Scale - Child Version in a clinical sample. Psychiatry and Clinical Psychopharmacology. 2017;27(1):84-92.
Owens JA, Spirito A, McGuinn M. The Children's Sleep Habits Questionnaire (CSHQ): psychometric properties of a survey instrument for school-aged children. Sleep. 2000;23(8):1043-1052.
Fis NP, Arman A, Ay P, et al. ÇocukUykuAliskanliklariAnketininTürkçegeçerliligivegüvenilirligi/The validity and the reliability of Turkish version of children's sleep habits questionnaire. Anadolu PsikiyatriDergisi. 2010;11(2):151-160.
Kucuksahin O, Omma A, Ozdemirel AE, et al. Incidence of sleep disturbances in patients with familial Mediterranean fever and the relation of sleep quality with disease activity. Int J Rheum Dis. 2018;21(10):1849-1856.
Sönmez AÖ, Sönmez HE, Çakan M, Yavuz M, Keskindemirci G, Ayaz NA. The evaluation of anxiety, depression and quality of life scores of children and adolescents with familial Mediterranean fever. Rheumatol Int. 2020;40(5):757-763.
Fredriksen K, Rhodes J, Reddy R, Way N. Sleepless in Chicago: tracking the effects of adolescent sleep loss during the middle school years. Child Dev. 2004;75(1):84-95.
Gujar N, Yoo SS, Hu P, Walker MP. Sleep deprivation amplifies reactivity of brain reward networks, biasing the appraisal of positive emotional experiences. J Neurosci. 2011;31(12):4466-4474.
Hysing M, Sivertsen B, Stormark KM, Elgen I, Lundervold AJ. Sleep in children with chronic illness, and the relation to emotional and behavioral problems-a population-based study. J Pediatr Psychol. 2008;34(6):665-670.
Valrie CR, Bromberg MH, Palermo T, Schanberg LE. A systematic review of sleep in pediatric pain populations. J Dev Behav Pediatr. 2013;34(2):120-128.
Palermo TM, Kiska R. Subjective sleep disturbances in adolescents with chronic pain: relationship to daily functioning and quality of life. J Pain. 2005;6(3):201-207.
Bloom BJ, Owens JA, McGuinn M, Nobile C, Schaeffer L, Alario AJ. Sleep and its relationship to pain, dysfunction, and disease activity in juvenile rheumatoid arthritis. J Rheumatol. 2002;29(1):169-173.
Tarakçi E, Arman SN, Barut K, Şahin S, Adroviç A, Kasapçopur Ö. Fatigue and sleep in children and adolescents with juvenile idiopathic arthritis: a cross-sectional study. Turk J Med Sci. 2019;49(1):58-65.
Spath Schwalbe E, Hansen K, Schmidt F, et al. Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men. J Clin Endocrinol Metab. 1998;83:1573-1579.
Taheri S, Austin D, Lin L, Nieto FJ, Young T, Mignot E. Correlates of serum C-reactive protein (CRP)-no association with sleep duration or sleep disordered breathing. Sleep. 2007;30(8):991-996.
Howren MB, Lamkin DM, Suls J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med. 2009;71(2):171-186.
Valkanova V, Ebmeier KP, Allan CL. CRP, IL-6 and depression: a systematic review and meta-analysis of longitudinal studies. J Affect Disord. 2013;150(3):736-744.
Duivis HE, Vogelzangs N, Kupper N, de Jonge P, Penninx BW. Differential association of somatic and cognitive symptoms of depression and anxiety with inflammation: findings from the Netherlands Study of Depression and Anxiety (NESDA). Psychoneuroendocrinology. 2013;38(9):1573-1585.
Alayli G, Durmus D, Ozkaya O, Sen HE, Genc G, Kuru O. Frequency of juvenile fibromyalgia syndrome in children with familial Mediterranean fever: effects on depression and quality of life. Clin Exp Rheumatol. 2011;29(69):S127-S132.
Tunca M, Akar S, Onen F, et al. Familial mediterranean fever (FMF) in Turkey: results of a nationwide multicenter study. Medicine. 2005;84(1):1-11.
Piram M, Frenkel J, Gattorno M, et al. A preliminary score for the assessment of disease activity in hereditary recurrent fevers: results from the AIDAI (Auto-Inflammatory Diseases Activity Index) Consensus Conference. Ann Rheum Dis. 2011;70(2):309-314.