Manipulation of Dietary Amino Acids Prevents and Reverses Obesity in Mice Through Multiple Mechanisms That Modulate Energy Homeostasis.
Journal
Diabetes
ISSN: 1939-327X
Titre abrégé: Diabetes
Pays: United States
ID NLM: 0372763
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
08
05
2020
accepted:
06
08
2020
pubmed:
12
8
2020
medline:
26
1
2021
entrez:
12
8
2020
Statut:
ppublish
Résumé
Reduced activation of energy metabolism increases adiposity in humans and other mammals. Thus, exploring dietary and molecular mechanisms able to improve energy metabolism is of paramount medical importance because such mechanisms can be leveraged as a therapy for obesity and related disorders. Here, we show that a designer protein-deprived diet enriched in free essential amino acids can
Identifiants
pubmed: 32778569
pii: db20-0489
doi: 10.2337/db20-0489
pmc: PMC7576563
doi:
Substances chimiques
Adipokines
0
Amino Acids
0
Dietary Proteins
0
Glucose
IY9XDZ35W2
Banques de données
figshare
['10.2337/figshare.12771341']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2324-2339Subventions
Organisme : NIDDK NIH HHS
ID : P30 DK058404
Pays : United States
Informations de copyright
© 2020 by the American Diabetes Association.
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