Fear of progression in parents of childhood cancer survivors: A dyadic data analysis.
cancer
central nervous system tumors
fear
leukemia
oncology
parents
pediatrics
psycho-oncology
quality of life
survivors
Journal
Psycho-oncology
ISSN: 1099-1611
Titre abrégé: Psychooncology
Pays: England
ID NLM: 9214524
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
12
03
2020
revised:
28
07
2020
accepted:
03
08
2020
pubmed:
12
8
2020
medline:
27
4
2021
entrez:
12
8
2020
Statut:
ppublish
Résumé
Fear of progression (FoP), also referred to as fear of cancer recurrence, is gaining increasing interest in survivorship research as it constitutes a great burden for patients and relatives. However, only little is known about FoP in parents of childhood cancer survivors. The objective of this study was to investigate the impact of FoP on quality of life (QoL) in parental couples. We analyzed dyadic data of 197 couples parenting childhood cancer survivors (aged 0-17 years at diagnosis of leukemia or central nervous system tumor) after the end of intensive cancer treatment. The actor-partner interdependence model calculated by structural equation modelling was used to examine actor effects (effect of one's own FoP on one's own QoL) and partner effects (effect of one's own FoP on the partner's QoL). Eighty-one percentage of the parents reported moderate or high FoP levels. Mothers reported higher FoP levels (p < .01) and lower overall QoL levels than fathers (p < .01). The results revealed a significantly positive intra-dyadic correlation between FoP of mothers and fathers of the same dyad (r = .431, p < .001). We found significantly negative actor effects for both mothers and fathers for the overall QoL (p < .001) as well as for several QoL subscales. No significant partner effects were found. Most parents reported elevated levels of FoP. Our results show that FoP in parents of childhood cancer survivors is strongly negatively associated with QoL. Parental FoP should therefore be explored in future research and needs to be targeted by health care providers.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1678-1685Informations de copyright
© 2020 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.
Références
Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev. 2010;36(4):277-285.
Kaatsch P, Grabow D, Spix C. German childhood cancer registry - annual report 2018 (1980-2017): Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI) at the University Medical Center of the Johannes Gutenberg University Mainz. 2019.
Ljungman L, Cernvall M, Grönqvist H, Ljótsson B, Ljungman G, von Essen L. Long-term positive and negative psychological late effects for parents of childhood cancer survivors: a systematic review. PLoS One. 2014;9(7):e103340.
Wakefield CE, McLoone JK, Butow P, Lenthen K, Cohn RJ. Parental adjustment to the completion of their child's cancer treatment. Pediatr Blood Cancer. 2011;56(4):524-531.
Kazak AE, Alderfer M, Rourke MT, Simms S, Streisand R, Grossman JR. Posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSS) in families of adolescent childhood cancer survivors. J Pediatr Psychol. 2004;29(3):211-219.
Simard S, Thewes B, Humphris G, et al. Fear of cancer recurrence in adult cancer survivors: a systematic review of quantitative studies. J Cancer Surviv. 2013;7(3):300-322.
Dinkel A, Herschbach P. Fear of progression in cancer patients and survivors. In: Goerling U, Mehnert A, eds. Psychooncology. Cham, Switzerland: Springer International Publishing; 2018:13-33.
De Graves S, Aranda S. Living with hope and fear - the uncertainty of childhood cancer after relapse. Cancer Nurs. 2008;31(4):292-301.
Ljungman L, Boger M, Ander M, et al. Impressions that last: particularly negative and positive experiences reported by parents five years after the end of a child's successful cancer treatment or death. PLoS One. 2016;11(6):e0157076.
Muskat B, Jones H, Lucchetta S, Shama W, Zupanec S, Greenblatt A. The experiences of parents of pediatric patients with acute lymphoblastic leukemia, 2 months after completion of treatment. J Pediatr Oncol Nurs. 2017;34(5):358-366.
Lindahl Norberg A, Green A. Stressors in the daily life of parents after a child's successful cancer treatment. J Psychosoc Oncol. 2007;25(3):113-122.
Schepper F, Abel K, Herschbach P, Christiansen H, Mehnert A, Martini J. Progredienzangst bei Eltern krebskranker Kinder: Adaptation eines Fragebogens und Korrelate [Fear of progression in parents of children with cancer: adaptation of the fear of progression questionnaire and correlates]. Klin Padiatr. 2015;227(3):151-156.
Clever K, Schepper F, Pletschko T, Herschbach P, Christiansen H, Martini J. Psychometric properties of the fear of progression questionnaire for parents of children with cancer (FoP-Q-SF/PR). J Psychosom Res. 2018;107:7-13.
Clever K, Schepper F, Maier S, Christiansen H, Martini J. Individual and dyadic coping and fear of progression in mothers and fathers of children with hematologic cancer. Fam Process. 2019;1-18. Epub ahead of print.
Clever K, Schepper F, Küpper L, Christiansen H, Martini J. Fear of progression in parents of children with cancer: results of an online expert survey in pediatric oncology. Klin Padiatr. 2018;230(3):130-137.
Peikert ML, Inhestern L, Krauth KA, et al. Returning to daily life: a qualitative interview study on parents of childhood cancer survivors in Germany. BMJ Open. 2020;10(3):e033730.
Vetsch J, Wakefield CE, Robertson EG, et al. Health-related quality of life of survivors of childhood acute lymphoblastic leukemia: a systematic review. Qual Life Res. 2018;27(6):1431-1443.
Litzelman K, Catrine K, Gangnon R, Witt WP. Quality of life among parents of children with cancer or brain tumors: the impact of child characteristics and parental psychosocial factors. Qual Life Res. 2011;20(8):1261-1269.
Klassen AF, Anthony SJ, Khan A, Sung L, Klaassen R. Identifying determinants of quality of life of children with cancer and childhood cancer survivors: a systematic review. Support Care Cancer. 2011;19(9):1275-1287.
Peikert ML, Inhestern L, Bergelt C. The role of rehabilitation measures in reintegration of children with brain tumours or leukaemia and their families after completion of cancer treatment: a study protocol. BMJ Open. 2017;7:e014505.
Von Elm E, Altman DG, Egger M, et al. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med. 2007;147(8):573-577.
Kenny DA, Kashy DA, Cook WL. Dyadic Data Analysis. New York, NY: Guilford Press; 2006.
Goldbeck L, Storck M. Das Ulmer Lebensqualitäts-Inventar für Eltern chronisch kranker Kinder (ULQIE) [ULQIE: a quality-of-life inventory for parents of chronically ill children]. Z Klin Psychol Psychother. 2002;31(1):31-39.
Kenny DA. Commentary: dyadic analyses of family data. J Pediatr Psychol. 2011;36(5):630-633.
Ledermann T, Kenny DA. Analyzing dyadic data with multilevel modeling versus structural equation modeling: a tale of two methods. J Fam Psychol. 2017;31(4):442-452.
Rosseel Y. Lavaan: an R package for structural equation modeling and more. Version 0.5-12 (BETA). J Stat Softw. 2012;48(2):1-37.
Stas L, Kenny DA, Mayer A, Loeys T. Giving dyadic data analysis away: a user-friendly app for actor-partner interdependence models. Pers Relat. 2018;25(1):103-119.
Kenny DA, Ledermann T. Detecting, measuring, and testing dyadic patterns in the actor-partner interdependence model. J Fam Psychol. 2010;24(3):359-366.
Goldbeck L. The impact of newly diagnosed chronic paediatric conditions on parental quality of life. Qual Life Res. 2006;15:1121-1131.
Schrank B, Ebert-Vogel A, Amering M, et al. Gender differences in caregiver burden and its determinants in family members of terminally ill cancer patients. Psychooncology. 2016;25:808-814.
Wickham RE, Macia KS. Examining cross-level effects in dyadic analysis: a structural equation modeling perspective. Behav Res Methods. 2019;51:2629-2645.
Herschbach P, Berg P, Waadt S, et al. Group psychotherapy of dysfunctional fear of progression in patients with chronic arthritis or cancer. Psychother Psychosom. 2010;79:31-38.