Keep Calm and the Placenta Will Carry On.

Animals DNA Damage De Lange Syndrome Female Mice Placenta Pregnancy

Journal

Developmental cell
ISSN: 1878-1551
Titre abrégé: Dev Cell
Pays: United States
ID NLM: 101120028

Informations de publication

Date de publication:
10 08 2020
Historique:
entrez: 12 8 2020
pubmed: 12 8 2020
medline: 14 1 2021
Statut: ppublish

Résumé

A fully functional placenta is critical for a successful pregnancy. In this issue of Developmental Cell, Singh et al. reveal that excessive placental DNA damage in murine models for Cornelia de Lange syndrome results in an inefficient and senescent placenta that impairs embryonic development.

Identifiants

DOI: 10.1016/j.devcel.2020.06.031 PMID: 32781021
pubmed: 32781021
pii: S1534-5807(20)30539-6
doi: 10.1016/j.devcel.2020.06.031
pii:
doi:

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

295-296

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Vicente Perez-Garcia (V)

Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK; Department of Physiology, Neuroscience and Development, University of Cambridge, Cambridge CB2 3EG, UK; Centre for Trophoblast Research, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.

Margherita Y Turco (MY)

Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK; Centre for Trophoblast Research, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK. Electronic address: myt25@cam.ac.uk.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Keep Calm and the Placenta Will Carry On.
questionsmedicales.fr › Phénomènes génétiques › Altération de l'ADN › Keep Calm and the Placenta Will Carry On.
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies génétiques congénitales › Maladies chromosomiques › Syndrome de Cornelia de Lange › Keep Calm and the Placenta Will Carry On.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Keep Calm and the Placenta Will Carry On.
questionsmedicales.fr › Structures de l'embryon › Placenta › Keep Calm and the Placenta Will Carry On.
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Keep Calm and the Placenta Will Carry On.