microRNA-646 inhibits angiogenesis of endothelial progenitor cells in pre-eclamptic pregnancy by targeting the VEGF-A/HIF-1α axis.

angiogenesis endothelial progenitor cells microRNA-646 preeclampsia vessel homeostasis

Journal

Experimental and therapeutic medicine
ISSN: 1792-0981
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 10 08 2018
accepted: 01 11 2019
entrez: 13 8 2020
pubmed: 13 8 2020
medline: 13 8 2020
Statut: ppublish

Résumé

Pre-eclampsia is a complication that occurs during pregnancy, the pathological feature of which is a change in vascular endothelial homeostasis. microRNA (miR)-646 is an anti-angiogenic miRNA that has been indicated to exhibit potential anti-angiogenic effects in endothelial cells cultured

Identifiants

pubmed: 32782496
doi: 10.3892/etm.2020.8929
pii: ETM-0-0-8929
pmc: PMC7401288
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1879-1888

Informations de copyright

Copyright: © Dong et al.

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Auteurs

Dirong Dong (D)

Department of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

Yimin Khoong (Y)

Department of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

Yunzhen Ko (Y)

Department of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

Yuanzhen Zhang (Y)

Department of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

Classifications MeSH