Screening of Bombyx mori brain proteins interacting with protein tyrosine phosphatase of BmNPV.
Bombyx mori
ELA
GST pull-down
PTP
brain
Journal
Archives of insect biochemistry and physiology
ISSN: 1520-6327
Titre abrégé: Arch Insect Biochem Physiol
Pays: United States
ID NLM: 8501752
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
25
04
2020
revised:
16
07
2020
accepted:
29
07
2020
pubmed:
13
8
2020
medline:
28
10
2020
entrez:
13
8
2020
Statut:
ppublish
Résumé
In this study, glutathione-S-transferase pull-down combined with mass spectrometry techniques were used to identify the candidate proteins interacting with protein tyrosine phosphatase of the Bombyx Mori nucleopolyhedrovirus in the B. mori (BmNPV-PTP) brain. A total of 36 proteins were identified from BmNPV-PTP coprecipitate samples by searching the NCBI_Bombyx Mori database with the original mass spectrum data. Among those proteins, the interaction between BmNPV-PTP and B. mori cyclophilin A may accelerate the apoptosis of certain nerve cells involved in regulating behavior, and thus may be an inducer of enhanced locomotor activity (ELA). After the BmNPV invasion, BmNPV-PTP binding to peripheral-type benzodiazepine receptors may initiate a series of abnormal cascades of the nervous system, which results in abnormal hyperactive behavior in B. mori. Besides this, vacuolar ATP synthase catalytic subunit A, annexin, and several enzymes for energy conversion were identified, which may play a role in enhancing viral entry and infectivity and provide energy for enhancing the locomotor activity of B. mori. In general, the results of this study will facilitate the understanding of the molecular mechanisms underlying the ELA of B. mori larva induced by BmNPV.
Substances chimiques
Insect Proteins
0
Viral Proteins
0
Protein Tyrosine Phosphatases
EC 3.1.3.48
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e21732Subventions
Organisme : Weifang University Doctor Startup Fund
ID : 2020BS26
Informations de copyright
© 2020 Wiley Periodicals LLC.
Références
Berri, F., Haffar, G., Lê, V. B., Sadewasser, A., Paki, K., Lina, B., … Riteau, B. (2014). Annexin V incorporated into influenza virus particles inhibits gamma interferon signaling and promotes viral replication. Journal of Virology, 88(19), 11215-11228.
Campiani, G., Ramunno, A., Fiorini, I., Nacci, V., Morelli, E., Novellino, E., … Williams, C. D. (2002). Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR). Journal of Medicinal Chemistry, 45(19), 4276-4281.
Cheng, Y., Wang, X. Y., Hu, H., Killiny, N., & Xu, J. P. (2014). A hypothetical model of crossing Bombyx Mori nucleopolyhedrovirus through its host midgut physical barrier. PLOS One, 9(12), e115032.
Dhingra, V., Li, X. Q., Liu, Y., & Zhen, F. F. (2007). Proteomic profiling reveals that rabies virus infection results in differential expression of host proteins involved in ion homeostasis and synaptic physiology in the central nervous system. Journal of Neurovirology, 13(2), 107-117.
Fouquet, B., Nikolic, J., Larrous, F., Bourhy, H., Wirblich, C., Lagaudrière-Gesbert, C., & Blondel, D. (2015). Focal adhesion kinase is involved in rabies virus infection through its interaction with viral phosphoprotein p. Journal of Virology, 89(3), 1640-1651.
Goulson, D. (1997). Wipfelkrankheit: Modification of host behaviour during baculoviral infection. Oecologia, 109, 219-228.
Gross, C. H., & Shuman, S. (1998). Characterization of a baculovirus-encoded RNA 5′-triphosphatase. Journal of Virology, 72(9), 7057-7063.
Heneberg, P. (2012). Finding the smoking gun: Protein tyrosine phosphatases as tools and targets of unicellular microorganisms and viruses. Current Medicinal Chemistry, 19(10), 1530-1566.
Hoover, K., Grove, M., Gardner, M., Hughes, D. P., McNeil, J., & Slavicek, J. (2011). A gene for an extended phenotype. Science, 333, 1401. 1401.
Houte, S. V., Ros, V. I. D., Mastenbroek, T. G., Vendrig, N. J., Hoover, K., Spitzen, J., & vanOers, M. M. (2012). Protein tyrosine phosphatase-induced hyperactivity is a conserved strategy of a subset of baculoviruses to manipulate Lepidopteran host behavior. PLOS One, 7(10), e46933.
Kamita, S. G., Nagasaka, K., Chua, J. W., Shimada, T., Mita, K., Kobayashi, M., … Hammock, B. D. (2005). A baculovirus-encoded protein tyrosine phosphatase gene induces enhanced locomotory activity in a lepidopteran host. Proceedings of the National Academy of Sciences of the United States of America, 102(7), 2584-2589.
Katsuma, S., Koyano, Y., Kang, W. K., Kokusho, R., Kamita, S. G., & Shimada, T. (2012). The baculovirus uses a captured host phosphatase to induce enhanced locomotory activity in host caterpillars. PLOS Pathogens, 8(4), e1002644.
Kawato, S., Yamada, M., & Kimoto, T. (2003). Brain neurosteroids are 4th generation neuromessengers in the brain: Cell biophysical analysis of steroid signal transduction. Advances in Biophysics, 37(1), 1-48.
Kim, D., & Weaver, R. F. (1993). Transcription mapping and functional analysis of the protein tyrosine/serine phosphatase (PTPase) gene of the Autographa californica nuclear polyhedrosis virus. Virology, 195(2), 587-595.
Liu, W., Li, J., Zheng, W., Shang, Y., Zhao, Z., Wang, S., … Sun, L. (2017). Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses. eLife, 6, e24425.
Peters, M. A., Jackson, D. C., Crabb, B. S., & Browning, G. F. (2002). Chicken anemia virus VP2 is a novel dual-specificity protein phosphatase. Journal of Biological Chemistry, 277(42), 39566-39573.
Provost, B., Varricchio, P., Arana, E., Espagne, E., Falabella, P., Huguet, E., … Drezen, J. M. (2004). Bracoviruses contain a large multigene family coding for protein tyrosine phosphatasesJournal of Virology, 78(23), 13090-13103.
Sheng, Z., & Charbonneau, H. (1993). The baculovirus Autographa californica encodes a protein tyrosine phosphatase. Journal of Biological Chemistry, 268(7), 4728-4733.
Takagi, T., Taylor, G. S., Kusakabe, T., Charbonneau, H., & Buratowski, S. A. (1998). Protein tyrosine phosphatase-like protein from baculovirus has RNA 59-triphosphatase and diphosphatase activities. Proceedings of the National Academy of Sciences of the United States of America, 95(17), 9808-9812.
Tian, H. Y., Hu, Y., Zhang, P., Xing, W. X., Xu, C., Yu, D., … Li, M. (2019). Spodoptera litura cyclophilin A is required for Microplitis bicoloratus bracovirus-induced apoptosis during insect cellular immune response. Archives of Insect Biochemistry and Physiology, 100, e21534.
Yang, S. L., Chou, Y. T., Wu, C. N., & Ho, M. S. (2011). Annexin II binds to capsid protein VP1 of enterovirus 71 and enhances viral infectivity. Journal of Virology, 85(22), 11809-11820.