Layer 4 organization and respiration locking in the rodent nose somatosensory cortex.

Rodents and other mammals acquire sensory information by precisely orchestrated head, whisker, and respiratory movements. We have, however, only limited information about integration of these signals. In the somatosensory domain, the integration of somatosensory information with other modalities is particularly pertinent for body parts such as eyes, ears, and nose, which serve another modality. Here we analyzed the nose/nostril representation in the rodent somatosensory cortex. We identified the representation of the nose/nostril in the rat somatosensory cortex by receptive field mapping and subsequent histological reconstruction. In tangential somatosensory cortical sections, the rat nostril cortex was evident as a prominent stripe-like recess of layer 4 revealed by cytochrome-